25f> Ccnthiuation of the Cowp&riaon of t/ie 



" ivTorc tlian a thousand subjects," says Mr. Duuninc'', 

 sunieoii a^ I'lvnio.jii-Dock* " have been vacct>ra/''d\u this 

 neighbourhood during the last year. Some hundreds of 

 thenj have fullcu to niy bharc. Complete .-'icccs* h.is been 

 invai iabU- in every case, where tlic vaccine character has been 

 unequivocally expressed. With a very lew exceptions, the 

 indi?pv)sition has been none at all, or the lea!<f nvuigiuablc, 

 and 1 know ot" no shade of accident that can fairly he attri- 

 buted to the new practice. In one child a very general and 

 obsiinatc cutaneous complaint, which had prtvinii:-ly resisted 

 much external and internal medicine, vcr\- soon disaf'pcarcd 

 after vaccination. Health and Jirmncss have shortly suc- 

 ceeded it in several weakly children, under my own observa- 

 tion, and 1 have heard of many similar occurrences : this ha* 

 mfflen snd ?'n sfyikiiiglu happened y that it has more than 

 once been proposed to me to vaccinate v/cj^/y children." 



4. Jji'sidcs li/nnoiirs which milituie agaimt the smnll-pox 

 inoculation, there ere variety nf diseases y which, if they at- 

 tack at the same time the child Jai'ouring wider the small- 

 pox, or soon after, u<iiialhj prove fatal: a corn bin atiov, hutv- 

 ei.'er, not found to become aggrcvated Inj, or increase, the 

 toil- pox. 



]^l\<ii, R , ;i vonng lady about five years old, was 



<cizcd, on the eveiung- of the eighth day after inocula- 

 tion with vaccine viruj», with such symptoms as conmionly 

 denote the accession of violent fever. Her throat was also 

 a little sore, and there were some uneasy sensations about 

 the muscles »)f the neck, 'i he Jay following a rash was 

 perceptible on her face and neck, so much resembling the 

 tfflorescence of rho scarlatina anginosa, that 1 was induced 

 to .ask Vvhethcr miss R- had been exposed to the con- 

 tagion ot tiiat disease. An answer in the alhrmative, and the 

 rapid spreading of the redness over the skin, at once relieved 

 mc from m'uh anx'ietv respecting llie nature of the malady, 

 which went iliroiigh it? course in the ordinary w.ay, but not 

 wiliU.ut svmptoms which were alarming, l-xith to myself 

 and Mr. Lyford, who atlcndcd w ith me. Tliere was no 

 apparent deviation in the ordinarv progress of the pustule to 

 a' state of maturitv, fron» what we see in gem-ral ; yet there 

 V,i!=i a total suspersion of iljc areola, or florid discoloration 

 around it, inuil \\\t scarlatina had retired from the constitu- 

 tion. As soon as the patient M-as freed from this disease, 

 thi-i appearance advanced in the usual way. 



'Ihe case of Miss H K is not less interesting 



thaij that of her sister ab;)\c related. She was exposed to the 

 2 coiitaiiiovi 



