Vaccine Institution, Broad-street. or 



of patients, as well as the furnishing of vaccine matter, □ 

 apply to No. 44, Broad-street. 



The medical establishment consists of Drs. Pearson. 

 hell, and Nelson, physicians; Messrs. Keate, Fay 

 ter, Heaviside, Gunning, Carpue, and Doratt, surgeons , 

 Messrs. Rivers, Brande, and De Bruyn, apothecaries. 



Wm. Sancho, Secretary. 



Dr. Pearson communicat ! r eral instances of failures 

 after vaccine inoculation, which, from the respectability of 

 the practitioners under whom they occurred, and the accu- 

 racy of their detail, must b>. admitted. He had been fortu- 

 nate in not, to his knowledge, having had, in his own prac- 

 tice, a single instance of small-pox after cow-pock ; but, 

 from what has of late happened, it would be unjust to 

 ascribe the exemption to any circumstance but an early 

 opinion that the vaccine disorder would require some years 

 to complete its investigation for secure practice, and hence 

 to u~e precautions not taken by those who represented the 

 subject as exhausted on its first promulgation. It is in vain 

 any longer to impute the failures to the matter taken beyond 

 the appearance of the areola; the use of a rusty lancet ; the 

 bursting of the vesicle; the use of " spurious matter"; the 

 susceptibility of tailing small-pox more than once, and there- 

 fore of small-pox after cow-pock; the using matter "de- 

 composed" by drying on a warmed lancet, or by the heat 

 of sealing-wax melted in sealing a letter containing matter; 

 the inserting the vaccine fluid into a wound deeper than the 

 skin, &c. &c. These circumstances served as bolsters to 

 prop up the practice by those who were cither too inexpe- 

 rienced to know, or did not possess candour to own, that 

 experience was wanting to determine the advantages of the 

 new practice. The publications in favour of vaccination are 

 written, for the most part, with the spirit of animosity and 

 not of investigation ; of course, they are not calculated to 

 Kmove doubts, and establish the vaccine p:actice< according 

 to its true value. On the other hand, the adverse writers 

 not at all anxious lor any thing but to collect and 



publish, 



