SS6 Vaccine Insfititilon. 



for the emperor of Japan is an ingenious piece of work- 

 manship carried I'roni England lu Russia by a German 

 named Schuri, and sold to the empress Catharine II. for 

 15000 roubles. It represents a peacock of the natural size, 

 which spreads out and folds together its magniticent feathers 

 ill a manner which exactly in)ita.lcs nature. It is accom- 

 panied by a great number of birds and small animals, which 

 all move with the greatest ease, and emit the sounds pecu- 

 liar to them. This beautiful automaton was placed formerly 

 in the Tauride palace, and imder Paul I. was removed to 

 the collection of rarities in the Hermitage. 



VACCINE INSTITUTIOX. 



The foUoiv'wg new Edition of Directions for the Vaccine 

 Inoculation has been lafeh/ issued by this Institution: 



I. The limpid matter should be taken from a decidedly 

 characterized cow-pock, which is proceeding, apparently, 

 through its respective stages. It is most efficacious in pro- 

 ducing the vaccina from a pock before the eleventh or 

 twelfth day ; and is most abundant, and is usually taken, 

 about the ninth day. But it may be used at an earlier 

 period, even as early as the iifth day, if it can be collected. 

 However, matter from a pock later than the eleventh or 

 tv.elfth days is not more liable to produce inflamed arms 

 than that from younger pocks ; and if the cow -pock be ex- 

 cited at all, it is as distinct as from any earlier matter. No 

 differences in the effects of the vaccine matter inoculated 

 appear to depend on the presence, extent, or absence of the 

 red areola. 



II. The matter is usually taken on glass, thread, or a 

 quill, on which it should be suffered to become dry with- 

 out applying heat, and when so dried it is scarcely visible. 

 The air should be excluded by keeping the matter betvveen 

 two glass plates, or in a bottle filled with hydrogen gas. 



III. As dried matter fails much more frequently to ex- 

 cite the vaccina than recent fluid matter, it will be advisa- 

 ble, in order to insure the effect, or for o1)taiuiug a great 

 quantity of matter, that. Instead of a single puncture or 

 scratch (which is sufficient and preferable with recent mat- 

 ter), there be matter inserted in two punctured or scratched 

 parts in each arm. The dried matter at the time of inocu- 

 lation should be softened by warm but not very hot water. 



IV. The inoculation must be performed in the same 

 manner as for the small-pox. 



V. If the infectious matter produce the required effect in 



three. 



