Sfl2 Original Vaccine Pock Institution. 



established in other places, and instructions for the practice 

 have been disseminated in every quarter of the world. 



*' With regard to the third part of the plan, the success 

 sion and the supply of matter ; as might be supposed, the 

 numbers inoculated in the years 1800 and JSOi v^'ere not 

 considerable. However, a register has been kept, and more 

 or fewer cases have been registered twice a week from Janu- 

 ary 1800 up to the present time; thereby affording a body of 

 evidence of very nearly two thousand patients, which have 

 been subjects of observation during this space of time. Such 

 a long and uninterrupted course of observation we apprehend 

 has no where else been pursued. The advantages for ob- 

 servation of even half a d(3zen patients a week, from 20O 

 to 220 weeks successively, over any gre;;ter tluiti the total 

 number here inoculated but in a few mou'ths or a few weeks, 

 can be well conceived by those who have ever been cm- 

 ployed in observation, and need not be explained. 



" It appears that not less than 12,000 parcels of matter 

 have been furnished by this institution ; and thereby it is es- 

 timated fairly, that not fewer than 60,000 persons havebeea 

 vaccinated with matter directly from this institution; be- 

 sides incalculable numbers from those so vaccinated. 



'' The whole pecuniary expense for these benefits 

 amounts to little more than three hundred pounds per an- 

 num : and although the subscriptions arc voluntary, and 

 Biostly of small annual sums ; and although the institution 

 has sustained crcat expenses, and pecuniary losses, chiefly 

 from unfortunately parting with moneys on a loan, and fronir 

 being obliiicd to change their house for the practice ; yet 

 there is a surplus of 530l. stock in the funds, and a respec- 

 table balance in the hands of the banker : and what is sur- 

 prising, is, that many persons have received rewards to sub- 

 mit to the test of smali pox inoculation, and others have 

 been relieved who were in distressed circumstances. 



" We appreliend there is not to be found in the con- 

 duct of any other institution, an example of even nearly so 

 •much benefit to individuals in particular, and society at 

 Jarge, at so small an expense. However, although it be 

 very true, that provided the present subscribers be pcrma- 

 jnent, the income will be adequate to the present expendi- 

 ture, it is not to be dissembled that the practice and inquiry 

 might be conducted upon a larger scale, and more agreea- 

 bly to the different officers, if their income would allow it. 

 Acccjfdingly, althoush it is not the plan of this meeting to 

 canvass for subscripcions, it is hoped that its friends will 

 thereby be augmented in such a manner as is thought pro- 

 per ; 



