314 Trogrefs of the Vaccine Inoculatien, and 



of the pra6lice, that the proportion of fatal cafes in the inr>- 

 culated fmall-pox, to the inoculated cow-pox, is as 10 to I, 



3. The conditutional affetlion, or fever, which occurs in 

 tlie cow-pox about the 9th day after inoculation, is much 

 more confiderablc in many cafes than was apprehended from 

 the (irft account by Dr. Jenncr, although in a great propor- 

 tion of Qafes it is extremcl\- llight, and in many cannot be 

 ofeferved at all. But I muft corrcft my ftatcmcnt in March 

 laft, in which I faid, " Ahhougli the extreme cafes of the 

 fcvere kind, which ordiioarily occur in the fame number of 

 cafes in the inoculated fmall-pox, did not occur in the new 

 praiStice, and although many of the patients were even more 

 ttrghtly difordered conftitutionally, yet the whole amount of 

 the conftitutional illnefs feemcd to be as great as in the fame 

 Kamber of patients in the inoculated fmall-pox." Since that 

 report, or at lead: for the lad four montlis, as far as I have ob- 

 ferved and been able to learn from others, the whole amount 

 ©f the conftltutional illnefs was not one half of the whole 

 amount in an equal number of patients inoculated for the 

 fmall-pox. Now, whether the greater mildnefs of the difeafe 

 depended on the different ftate of the human co.iftltution in 

 the fummer from that of winter, as feems to me moft pro- 

 bable ; or that it depended on the difference in the ftate of 

 the vaccine matter, muft be determined by future experience 

 in the fame feafons. 



3. The moft remarkable difference in the praftice of the 

 Jaft winter, and prefent fummer, has been with regard to the 

 eruptions which fo often occurred, efpecially in the SmalU 

 pox Hofpital; which eruptions, in many inflances, could not 



fbns in proportion have died of the inoculated fmall-pox within a few 

 years, tlian died in the fame time 20 years ago. And tiiis may be account- 

 ed fc.i fro'.u the unwarrantible alTertions of many iiioculators, fom whom 

 a great part nf tbe pubii; Iiivc imbibed the opinion, that the inoculated 

 fm:ill-pox was^^not ottended with any danger; hence the praftice is ofteit 

 tnifted in the hnids of perfons not fufficiently acquainted with the treat- 

 Bvput &t for difleienx dates of the human conflitutioQ. 



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