JExpermenls refpfSing the Vacctne Dlfeafe. 519 



tine matter by paffing it through the fkin. On viewing the 

 arms in three days time^ that with the thread appeared in- 

 flamed, (liowing a red elevated fniall fpot; the other arm, w liich 

 had been puntlured, barely fliewed a red mark. The punctures 

 had fniarted for about twenty-four hours, but no other effects 

 were produced. Thcfe red fpots difapp'eared in a few^ days. 



In three weeks further the inoculation was again infti- 

 tuted, but with fluid lymph applied, immediately from the 

 puftule of a patient prefent, to pun6tures in each arm. More 

 fmarting and more inflammation were produced by this in- 

 oculation than by the former. A i'mall quantity of pus was 

 produced in the little red fpots from the punctures in about fix 

 or feven days, but no diforder arofe in the whole coiifl:itution, 



Mr. Dangcrfield w-as next inoculated in one arm with 

 variolous matter. In the evening of the day of inoculation 

 inflammation appeared, which increafed to a greater degiee 

 and extent than from the vaccine inoculations. A fmall 

 phlegmonic tumor in the part inoculated with variolous 

 matter continued for a fortnight, during which time it, 

 fuppurated, and the pus from it did not heal in lefs than 

 t iree weeks further. There was no conftitutional affection ; 

 bjt tliere was pain in the arm-pit in about five days from 

 the inoculation. 



a. Mr. Pollock was inoculated in each arm with a lancet 

 armed with fluid matter immediately on taking it from a 

 patj^nt. A little fmarting was felt for a day or two, and the 

 parts inoculated were red for feveral days j but no pufl;ule9 

 arofe, nor conftitutional afTeition. 



3. Mr. Perkins was inoculated by pun6iuring one ariu 

 ..ith a hnicct ftained with recent vaccine matter, and tha 

 uier was inoculated with variolous matter. A, red fpot was 

 iLcn on each of the parts inoculated the day following; aa4 

 an itching fcnfation, efpecially from the vacc?iu; matter, waa 

 experienced for a day or two. The parts remained elevated 

 and inflamed a little for a few days further, and then pit 

 9 well 



