Experiments ref, eclhig the Vaccine Difeafe, 3'?i 



lytnph from a fubjeft prefent. The punftured part fmarted 

 a little all the remainder of the day of the inoculation, and 

 alfo the day following. In twenty-four hours a red fpot on 

 the inoculated part was feen exactly like that which is often 

 feen in the fame time when either the vaccine or variolous 

 infeftion has taken effeft, and which increafed for another 

 day; but after this the rcdnefs vanifhed, ar>dno fore was left. 

 . I once accidentally punftured the back of my hand with 

 a lancet which had fluid vaccine matter upon it. The con- 

 fequence wa?, a circumfcribed, very fmall, red, hard tumor : 

 this remained for a fortnight, then fuppurated, and after- 

 wards burft. The part foon healed, but left a very fmall 

 fuperficial cicatrix. 



As belonging to this head, I mention, that I have feen fe- 

 veral inftances of nurfes having fmall, red, conical tu i:!ori 

 on their lips and cheeks, and fometimes hands ; evidently 

 from the application of cow-pox matter of the children under 

 their care during the vaccine inoculation. Thefe little tumors 

 fometimes remained for feveral weeks^ and a particle of pus 

 was formed in them : they never were attended by any fever 

 fymptoms, nor by any furrounding erythematous areola. — I 

 here fpeak of nurfes who had long before pafled through the 

 fmall -pox. 



I have no hefitation to refer the follovl'ing cafes to this 

 head of unfufccptibiiity of taking the cow-pox to having pre- 

 vioufly gone through the finall-pox. 



A fervant of Thomas King, Efq, about i8 years of age, 

 was brought up during his infancy under circumftanccs in 

 which he could get no teflimony to his having had, or not 

 having had, the fmall-pox. Not having undergone this dif- 

 eafe to his own knowledge, it was thought advifeable, in 

 order to refifl the fmall-pox, with which his fellow-fervant 

 was feized, to inoculate him for the cow-pox. This I did on 

 Thnrfday the 23d of Margh, in one arm with matter on a 

 lancet, and in the other with dried matter on a hit of thread. 



4//' Dnji, Sunday 26. Ihc parts inoculated had fmarted 

 Vol. IV. Y for 



