9* Paccine Inoculation. 



VACCINB INOCULATION. 



An eftabliniment has lately been formed at Pans for ^h? 

 vaccine inoculation. " A trial of the vaccine inoculation," 

 fays a letter from Paris, dated June 3, " was begun her? 

 yefterday. Thirty children were inoculated with matter re- 

 ceived from London, and according to the direftions given 

 by Dr. Pearfon. The matter was tranfmitted hither in phials 

 filled with hydrogen gas clofed by mercury, and covered with 

 a piece of bladder. The greater part of thefe children were 

 inoculated with the matter on lancets, which Dr. Pearfon 

 recommended as moft efficacious ; fome of them with 

 threads, applied by means of veficatorics ; and a fmall 

 number with matter collefted on glafs. A daily report 

 will be given of thefe trials, which are made at Vaugirard, 

 the houfc of C. Colon, at which the members of the me- 

 dical committee are to meet every day at one in the after- 

 noon." 



The following letter on this fubje6l from Mr. Stromeyer, 

 of Hanover, to Mr. Hannehmann, dated 24th March laft, 

 contains fome further information refpefting the ftate of vac- 

 cine inoculation on the Continent : 



" This year we have inoculated forty perfons, as well with 

 the vaccine matter received of Dr. Pearfon, as with that from 

 Dr. Jennerj all of whom underwent the difeafe properly. 



*' Betwixt the London and Gloucefter vaccine matter, it ap- 

 pears to me there fubfifts an eflenlial difference. The London 

 matter produces frequently an eruption of fmall pimples, but 

 they difappear within a day or two at furtheft. Dr. Pearfon 

 calls thefe eruptions pujhihs. The Gloucefter matter has 

 never produced this effed here; but it frequently occajioned 

 ulcerations of the inoculated fart ^ of a tedious and long dura- 

 tion^ ^uhich the former matter never did; ori account of which 

 I now only make ufe of Dr. Pearlon's vaccine rnatter. 



" The nettle-fever-Iike eruptions I have obferved feveral 

 times, but never that fort of eruption, repeatedly noticed iif 

 London, which fo much refembles the fmull-pox. 



** Of all thofe I have inoculated, none of them were feverely 



ill during the difeafe. Their general fymptoms v/ere, a (light 



9 ' fever, 



