3r8 Otjfervations refpecting the Earthquake 
from the experience I have had, no practitioner can anfwer — 
for fuch cafes not occurring in any inftance, and as danger 
is always in proportion to the number of eruptions, which 
number no one can pretend to limit, it is evident that the 
chance of life during this difeafe is leffened, although but a 
very little. Provided this flatement be made to the patient, it — 
does not appear to me that the fact of the liability to eruptions 
‘ought to impede the progrefs of the Vaccine Inoculation; 
but if, on the contrary, the patient is affured that fuch erup- 
fions will not occur, there is good ground for the practice 
falling into difcredit, or at leaft for many perfons, with rea- 
fon, being difeontented. 
After this réprefentation of an unfavourable part of the 
hiflory of the cow-pock, it is confolatory to be able to coun- 
terpoife it with fome new faéts, which, hke that of the erup- 
tions, have been difcovered in the courfe of further experi- 
ence. It now appears that a perfon who has had the fimall- 
pox, is not fufceptible of the cow-pox by imoculation* ; 
nor is a perfon fufceptible of the conftitutional affection from 
_ the cow-pox poifon more than once. On the whole, then, 
we have gained perhaps as much as we have loft finee the 
publication of the original account: and unlefs fome new 
adverfe facts fhall be difcoyered, and confiding that the public 
will adopt a practice which is fo manifeftly to their intereft, 
the change effected in the pra¢tice of medicine will be fo 
eminently memorable, that the introduétion of the Vaccine 
Inoculation mufl become an epoch in the biflory of phyfic. 
I. Obfervations refpeéiing the Earthquake which took place 
in Peru in the year 1797. By M. CAVANILLES*. 
¢ en are reckoned to be more than fixteen volcanoes 
in the kingdom of Quito which are in a-continual ftate of 
eruption, and which throw up thick vapours, often mixed 
* The cafes of milkers with chopt hands being repeatedly affected by 
the cow-pox poifon in the cafval way, wheter they had undergone the 
fmall-pox or not, probably occafioned the error of the conclufions here 
alluded to. 
+ From the Yournal de Phyfique, Fractidor an. 7, b 
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