3"o8' On the Vaccine Inoculation. 



upon the publication of a work that mud throw the greateft 

 light on a fubjeft which engages now the attention of all 

 civilifed nations. Whenever my materials mall be fufficient, 

 I purpofe writing a complete treatife on the fubjeft for the 

 ufe of the continental phyfieians, and fuch perfons as are not 

 in the way of collecting from the various fources of informa- 

 tion which a little zeal and activity have opened to me. 



I have the honour to be, -. 



Dear Sir, 

 With the fincercft efteem, 

 Your mod obedient humble fervant, 



J. DE CARRO. 

 P. S. I fent lately fome vaccine matter to Lord Elgin at 

 Conltantinoplc for the inoculation of his only fon. 



III. letter from John Branson, Efq. Surgeon, to 

 Dr. Pearson, on the Vaccine Inoculation. 



I 



DEAR SIR, Doncafter, Nov. 23, 1803-. 



N aw lad letter 60 you I mentioned my ideas refpefting 

 [be infufceptibiliiy of tic vaccine contagion to a perfon ivho 

 bad prcviou/ly bad the fmall-pox. I am ftill of the fame 

 opinion, as I have never vet been able to produce the true 

 vaccine puftule in a perfon who had before undergone the 

 fmall-pox ; but I have lately had a cafe from which it would 

 appear that, if both difeafes are introduced into the fyftejn 

 about the fame time, they will both be received, and proceed 

 through their regular flakes, without beinc; at all affefted bv 

 each other. A child was inoculated for the cow-pock, after 

 it had been for fome days expofed to the contagion of the 

 natural fmall-pox, on Fridav the 26th of September. The 

 arm went on in the ufual way till Wednefday evening fol- 

 lowing, when the child was fcixed with fever, and in tha 

 evening of the next dav the fmall-pox appeared. The erup- 

 tion was confluent, and particularly io about the inoculated 

 part, on Monday the 6th of October, which was the eleventh 

 day from the inoculation of the vaccine matter, and the fifth 

 ttom the commencement of the fever of the fmall-pox. I 

 8 inoculated 



