.310 On the Vaccine Inoculation. 



Since the month of September, when I returned from 

 Boulogne, I have inoculated for the vaccine 160 fubje&s of 

 all ages, but the greater part children. All thefe different 

 experiments, which were attended with the greateft fuccefs, 

 have invariably difplayed that character of mildnefe which 

 eitablifhes, in an incontestable manner, the fuperiority of the 

 new over the old mode of inoculation ; and the difference 

 which we have had an opportunity of remarking in fome of 

 the refulls tends ltill further to confirm this fuperiority. 



All the children and adults whom I inoculated during the 

 whole courfe of the experiment continued their ufual fports 

 and exercifes without feeling the lead inconvenience. The 

 adults followed their daily occupations, and in general ex- 

 perienced a very {hort fenfation of uneafinefs, and at mod a 

 flight febrile affection. 



Six weeks alter my firft experiments I made fucceffively 

 feyen counter-experiments. I carried to the houfe of 

 C. Bcaufoleil, whofe children were attacked with the na- 

 tural fmall pox, the eruption of which was very abundant, 

 three children of C. Beugne, who had been inoculated with, 

 the vaccine. After leaving them a long time together, I 

 inoculated my three fubjecls, as ufual, with the variolous 

 matter taken from the youngett of the children, who was 

 covered with the eruption ; but none of them experienced 

 the leaft effect from the operation. 



The other four fubjecls, whom I afterwards fubje&ed to » 

 counter-experiment, were, a young domeftic of C. Wynne, 

 another of G. Bell, and two fillers of the latter. I carried 

 them to the houfe of C. Trudin, broker, whofe child had 

 the natural fmall-pox. They were all inoculated without 

 the leaft effect. 



C. Magnier, of Pont-de-Brique, having fent for his fon 

 from Boulogne, where he was at fchool, I inoculated him 

 with the vaccine in the country. He was then fent back to 

 fchool, where the fmalUpox had broken out during his ab- 

 fence. The young man continued as ufual to frequent the 

 company of his fchool-fellows infected with the contagion, 

 to play with them, to eat with them, and to fleep in the 

 fame room with thenij without experiencing any effect. 



I haye 



