154 Report of the National Vaccine Establishment. 



Henry HaUbnl and Sir Waller Favquhar, the physicians who 

 attended tlic young gentleman during his ilhiess; and the 

 case of the son of Sir Henry Martin was obtained throngh 

 the favour of Dr. Hebcrden. Both of these cases were also 

 visited by the Director uf the Vaccine Establishment. 



I. The Case of the Hon. Robert Grnsveiior. 



On Sunday, May 20, 1811, the Hon. Robert Grosvenor, 

 who was recovering froin the hooping-cough, became much 

 indisposed, and threw up his dinner. Fever followed, and 

 he complained most particularly of excruciatinff pain in his 

 back. He dwelt on this symptom until Thursday, when he 

 became delirious, and there were observed on his face about 

 tuenty spots. 



He had been vaccinated bv Dr. Jcuner, in his infancy, 

 about ten vears ago, and the mark left in his arm indicated 

 a perfect disease. 



On Fridav morning, the eruption had not increased ma- 

 teriallv in point of number; but the appearance of tiie spots, 

 and the previous symptoms, suggested strongly a suspicion 

 that the disorder was the small-pox. 



Sir H. Halford had occasion to go to Windsor in the af- 

 ternoon of Friday, and did not see Mr. Robert Grosvenor 

 until the Monday following (June 2d); but he learned from 

 SirW. Farquhar, w ho attended him most carelully during Sir 

 Henry's absence, (and subsequently,) that the eruption had 

 increased prodiijiously in the cour^sc of Fririay ; that on the 

 evening of that day Mr. Robert Grosvenor began to make 

 bloody water, and that he continued to do so until Monday 

 morning. 



On the tenth day of the disease the pustules began to dry 

 upon the face, which was swollen to a considerable degree, 

 but not to the extent of closing his eyes, and was attended 

 by a salivation, which lasted several days. Pelechiai had 

 occurred in the interstices of several of the spots, particu- 

 larly on tlic limbs, and there was that particular smell from 

 the whole iVame n inch is remarkable in bad cases of con- 

 fluent suiall-pox. 



It was obvious that the first symptonis of which Mr. 

 Grosvenor conuilained, were such as indicated a violent dis- 

 ease about to follow ; and Sir Henry conlesses that he cn- 

 levtained a most unfavourable opinion of the issue of such 

 a maladv, when it was fully formed ; having never seen an 

 instance of recovery under so heavy an eruj)lion attended 

 hv such circuiMSiances. It seemed, however, that the latter. 

 sta<^es of the disease were passed through more rapidly io 



^ " ' thisi 



