156 Report of the National Vaccine Estallishmcnt. 



8th The pustules were dried, and continued to fall off 

 from ihe face. The boy continued cjnite vveil. 

 Pall Mali, July 4, ISll. VV. HeBERDEN, 



With a view of obtaining the most accurate knowledge 

 of the early symptoms of this case, which did not come 

 under ihe immediate observation of Dr. Hcberden, the Board 

 have procured, tlirough the favour of Mr. Tegart, of Pall 

 Mail, an account of tiie comnuncement and course of the 

 disorder, which corroborates the above statement. And 

 from the same source they have been informed, thai Miss 

 Martin and a nurserymaid of Sir H. Martin's family, who 

 had both been v?.cclp.ated, were inoculated wiih matter taken 

 from Master Martin on the fifth day of the eruption, and 

 were exposed to the contagion of the small-pox daring the 

 course of his disorder, without efl'ect. 



The Board are of opinion, that the case of the Hon> Ro- 

 bert Grosvcnor was a case of confluent small pox. That 

 the attack and progress of the disorder were attended by 

 symptoms which almost invariably announce a fatal termi- 

 nation. But they observe, that the swelling of the face, 

 which is generally so excessive as to close the eyes, and is 

 considered as a favourable sympujm, was slighter than 

 usual ; that on the tenth day the pustules began to dry upon 

 the face; and that from that time the disease passed with 

 unusual rapidity through the period when life is generally 

 esteemed to be in the greatest hazard. 



Those who are acquainted wiih the nature of the con- 

 fluent small-pox, are aware that this peculiarity cannot be 

 attributed to the effect of medical treatment. 



The case of the son of Sir Henry Martin exhibits a mild 

 form of distinct small-pox occurring after vaccination, j 



In most cases oi small-pox whlcii have succeeded to vac- 

 cination, the pustules have been observed to dry more ra- 

 pidly, and the disorder has concluded at an earlier period 

 than usual. 



If allowance be made for the relative periods in which 

 the confluent and distinct small-pox con!j)Ietc liieir course, 

 the ra[)id progress towaids recovery tbroueh the latter stae;e 

 of confluent small-pox, as exhibited in the case of Mr. 

 Grosvenor, may be compared with the rapid desiccation of 

 the pustules in the distinct and peculiarly mild i'orm of the 

 disorder which is considered as sinall-pox modilied l)y vac- 

 cination. Both lorms of the disorder proceed in the usual 

 course, the one attended with violent, tlie other with mild 

 symptoms^ till ih'.yarri\e near to the height; when they 



appear 



