Report of the National Faccine Establishment. 157 



appear to receive a check, and the recovery is unusually 

 rapid. 



From this correspondence of circumstances, the Board 

 are induced to infer that in the case of Mr. Grosvenor, 

 which has been more violent than any yet submitted to 

 them, the progress of the disease, through its latter stage, 

 and the consequent abatement of symptoms, were in- 

 fluenced by an autivariolc^us effect produced upon the con- 

 stitution by the vaccine process. 



The occurrence of small-pox after vaccination has been 

 foreseen and pointed out in tlie Report on Vaccination made 

 to Parliament, bv the College of Physicians, in the year 1807, 

 to which the Board arc desirous of calling the attention of 

 the public; wherein it is stated that, 



"The security derived from vaccination against the small- 

 pox, if not absolutely perfect, is as nearly so as can perhaps 

 be expected from any human discovery ; for amonost several 

 hundred thousand cases, with the results of which the Col- 

 lege have been made acquainted, the number of alleo-ed 

 failures has been surprisingly small, so much so as to form 

 certainly no reasonable objection to the general adoption of 

 vaccinatiim ; for it appears that there are not nearly so many- 

 failures in a given number of vaccinated persons, as there 

 are deaths in an equal number of persons inoculated for the 

 small-pox. Nothing can more clearly demonstrate the 

 superiority of vaccination over the inoculation of the small- 

 pox than this consideration ; and it is a n)ost important 

 fact, which has been confirmed in the course of this in- 

 quiry, that in almost every case in which the small-pox has 

 succeeded vaccination, whether hy inoculation or by casual 

 infection, the disease has varied much from its ordinary 

 course; it has neither been the same in violence nor in the 

 duration of its svmptoms; but has, with verv few exceptions, 

 been remarkably mild, as if the small-pox had been deprived 

 by the previous vaccine disease of its usual malignity. "— 

 Vide Report of the College of Physicians. 



The peculiarities of certain constitutions with regard to 

 eruptive fevers, form a curious subject of medical history. 

 Some individuals have been more than once affected with 

 scarlet fever and measles, others have been ihroutrh life ex- 

 posed to the contagion of these diseases withoiit effect* 

 many ha\'e resisted the inoculation and contagion of small- 

 pox for several years, and have afterwards become suscepti- 

 ble of the disorder, and some have been twice affected with 

 «mall-pox. 



Atuong such infinite varjetie? of temperament it will not 



appear 



