430 Some further Observations on the Use of 
was quite well, and has continued so a period of more that three 
months. 
The result of this case satisfied me that the infusion contained 
the specific remedy for the gout, and that the deposit is not ne- 
cessary for its removal, 
This rendered it probable that, where the deposit is taken 
along with the infusion, its solid form prevents it from being 
carried into the cireulation of the blood, and it remains in the 
stomach, producing more or less mischief in that viscus, without 
being any way concerned in driving away the disease "st which 
the medicine was exhibited ; in this respect resembling many of 
the salts of mercury, which irritate the bowels, without relieving 
the syinptoms of the venereal disease. 
I explained these opinions to Mr. Gatconibe, who gives me 
his assistance in my professional pursuits, and requested him to 
investigate this subject. 
To do this more completely, he began by repealing the three 
experiments detailed in my former paper, substituting the Eaw 
Medicmale for the vinous infusion of Co/chkicum, so as to de- 
termine with more precision whether they are or are not the 
same medicine. 
Exp. \. Thirty drops of the Eau Medicinale with the de- 
posit were injected into the jugular vein of a dog; the effects: 
were the same as in my experiment with the same quantity of 
the vinous infusion of Colchicum, only the animal was two hours 
longer in recovering from them, and was purged for nine hours 
afterwards. 
Exp. 2. Sixty drops of the Eau Medicinale were given by 
the mouth to the same dog: the effect was less than in my ex- 
periment with the vinous infusion of Colchicum exhibited in the 
same quantity: this arose from a very copious evacuation of 
urine having been produced. 
Exp.3. One hundred and sixty drops of the Eau Medicinale, 
injected into the jugular vein of a dog, produced rather more 
violent effects than in my experiment with the same quantity of 
vinous infusion of Colchicum; the animal died in six hours, and’ 
after death the appearances of inflammation in the bowels were 
moie violent, approaching to mortification. 
Mr. Gatcombe having found so exact a similarity in the ef- 
fects of the two medicines, in these trials, | requested him to 
make the following comparative experiment on the effects pro- 
duced upon the stomach and bowels by the /:au Mediciale, in 
which there is a deposit, and the vinous infusion of Colchicum, im 
which there is none, 
Exp. 4. One hundred and sixty drops of the Eau ao 
taken 
