3')'2 Report of the National Fucclne EslaMhliment 



great numbers of persons who had l)een vaccinated, have heen 

 subsequenllv seized with a disease presenting al! the essential 

 characters of sniall-pox ; but that in the great majority of such 

 cases, the disease lias been of comparatively short duration, un- 

 attended bv svm|)toms of danger. In several of these cases, 

 however, the malady has lieen prolonged to its ordinary j)eriod ; 

 and in ciglit reported cases it has proved fatal. 



It appears to us to be fairly established, that the disposition in 

 the vaccinated to be thus aifccted by the contagion of small-pox, 

 does not depend on the time that lias elapsed after vaccination ; 

 since some persons have been so aftected who had recentlv been 

 vaccinated; wiiilst others, who had been vaccinated IS and 20 

 years, have been inoculated, and fairly exposed to the same con- 

 tagion with impunity. 



Nor is it undeserving of remark, that whilst cases of small- 

 j)ox in the vaccinated have frecjuently been reported to us, from 

 some parts of the kingdom remote from the metrojiolis, no cases 

 of a similar nature are k«own to have happened in other districts 

 equally populous. Very intelligent surgeons in the different 

 counties of Norfolk, Devonshire, Middlesex, Cheshire, and Staf- 

 fordshire, who to{?ether have vaccinated more than 30,000 per- 

 sons, assert that they never saw or heard of small-pox in any 

 one of tbeir vaccinated patients. 



But no assertions of individuals, however res])ectable, are so 

 well calculated to direct the judgement of your Lordship as the 

 registers of public charities. 



The practice of vaccination was begun in the Small-pox Hos- 

 pital of London in the ycnr 1799, soon after the promulgation 

 of Dr. Jenner's discovery, and has been continued lo the pre- 

 sent dav. In the last annual Report it is stated by Dr. Ash- 

 burner, " That the benefit of vaccination has been extended 

 within the year to 3,2i)7 persons ; that one only of tlie 4G,6(i2 

 cases mentioned in former Reports, has been since affected with 

 the varioloid eruption occurring after vaccination." 



At the Foundling Hospital, vaccination was introduced nine- 

 teen vears ago; and we are informed by Dr. Stanger, that only 

 two cases of disease bearing any resemblance to small-pox have 

 hitherto occurred in tlic vaccinated of that institution. 



Mr. MacGregor issures us, that in the great assemblage of 

 the sons and daughters of soldiers who are brought ifp at the 

 lloval Military Asylum, no case even of the mildest small -pox 

 has ever occurred after vaccination. 



Under the immediate direction of the National Vaccine Esta- 

 blishment, more than fJO,000 persons have now been vaccinated 

 in London and its vicinity ; and of this large number only five 

 arc reported to have been subsequently aifccted witli small-pox ; 



although 



