Gland-Cells of Internal Secretion in Spinal Cord of Skates. t 
hematoxylin, but taking mucicarmine and Delafield’s hematoxylin very 
deeply. The corresponding achromatic nuclear content of the muscle 
motor cells does not act so with regard to mucin stains and on the same 
slide is clear or takes an acid counterstain like eosin. With a Dela- 
field hematoxylin stain the chromatin contents of the nucleus are 
masked or entirely hidden by the deeply staining nuclear sap. Witha 
bulk stain like borax carmine it also stains deeply, while in the muscle 
motor cells it shows no staining power. With the Pal-Weigert stain- 
ing method the chromatic substance of the nucleus becomes a deep 
brown. The chromatin of the muscle motor nerve-cells, however, 
remains unstained. It is clear from these reactions that the nucleus 
contains a chromatic constituent not found in the nerve-cells of this 
animal. 
The size or volume of this nucleus is large even in proportion to the 
immense bulk of the cell. The central area alone approximates in 
size the large nuclei of nerve-cells in the same sections. Each of the 
numerous terminal portions of the various branches alone is larger than 
the central portion, and if the whole nucleus were to be concentrated 
into the usual spherical form it would certainly be among the largest 
nuclei known. 
When well-fixed Flemming material is stained with a sharp regressive 
stain like iron hematoxylin, the real chromatic material of the nucleus 
comes out strongly, and we find that the largest quantity of such 
material consists of very numerous, evenly distributed granules of con- 
siderable size. This size is fairly even and uniform for the larger par- 
ticles, and scattered among them are very small particles together with 
a few intermediate in size. All parts of the nucleus possess these 
granules, except sometimes the central area of the nucleus, which may 
be almost clear. In many cases one or two much larger chromatic 
bodies are found in the central area or in that part of one of the branches 
nearest to it. These chromatin particles are not round bodies, although 
they are compact. They are elongate to varying degrees, but can not 
be called rod-like. While they are also irregular in shape, their out- 
line is smooth and not jagged or rough, except in a few cases. 
The cytoplasm of these cells was quite homogeneous in character 
when found at rest. That it had a chromophilic content was quite 
apparent, for it stained with the proper stains and to sufficient depth 
to show this. But in no specimen was this shown to be organized into 
Nissl granules. In the neighboring motor nerve-cells the chromophilic 
substance is plainly visible as Nissl granules which are assembled at or 
near the periphery of the cell in the form of typical tigroid bodies. 
Furthermore, the general color of the cytoplasm outside these tigroid 
bodies is far lighter than the cytoplasm of the large cells in question. 
No definite neurofibrils are present. It was thought at first that 
with the proper stains some of the many processes of these cells might 
