54: Royal Society :— 
“¢ Division, on both sides of the neck, of the ascending branches of 
the superior thoracic ganglion which run up towards the canal 
formed by the foramina in the transverse processes of the vertebree, 
for the vertebral artery, occasions an intensely marked diabetes. The 
urine has been found most strongly saccharine within even half an 
hour after the operation. The diabetic condition is only of a temporary 
character, passing off by the next day, and fatal pleurisy is always 
induced. 
“Division of the ascending branches of the superior thoracic 
ganglion on one side of the neck only, has occasioned merely the 
presence of a trace of sugar in the urine in an hour and a half’s time. 
The same operation then performed on the other side has produced 
in half an hour’s time an intensely saccharine urine. 
“ Carefully ligaturing the two vertebral and the two carotid arte- 
ries does not lead to saccharine urine ; but when the carotids have 
been tied, and the tissue in connexion with the vertebrals before their 
entrance into the canals is a little roughly treated, without however 
dividing the larger sympathetic filament ascending from the superior 
thoracic ganglion, the urine is rendered rapidly and strongly saccha- 
rine. 
“Division of the sympathetic filaments that have entered the 
canals does not alone produce diabetes; but if the contents of 
these canals be divided, and the carotid arteries at the same time 
ligatured, saccharine urine is the result. 
‘This result is produced when the contents of the osseous canals 
are divided as high as the second cervical vertebra. It has also arisen 
after destroying the structures in the neighbourhood of the vertebral 
foramen on the posterior surface of the transverse process of the atlas, 
but has not yet been noticed after a similar operation on the anterior 
surface of the process. 
‘Dividing the contents of the canals and the tissue in immediate 
contact with the carotid vessels has not produced diabetes; but when 
the carotids have been afterwards tied, strongly saccharine urine has. 
resulted. 
“ Of all the operations on the sympathetic of the dog that have yet 
been performed, removal of the superior cervical ganglion the most 
rapidly and strongly produces diabetes. After the removal of one 
ganglion, the urine has been found intensely saccharine in an hour’s 
time, and the saccharine character has remained during the following 
day, but has disappeared by the next. Subsequent removal of the 
other ganglion a few days later has been followed in half an hour’s 
time with a strongly marked diabetic effect, which, however, has 
been again only of a temporary nature. 
** Division of the sympathetic in the chest has been several times 
succeeded by saccharine urine. In one case after division on one 
side only, the urine was intensely saccharine in half an hour’s time. 
On the other hand, many experiments have been made where both 
sides have been operated on, and only a merely traceable, or in a 
few instances, even no effect, has been noticeable. 
“In the rabbit, removal of the superior cervical ganglia, when 
