into the Isles of France and Reunion. 'tS 



relative to this practice in the United-States ; but / 

 hope it ml! become universal ; that^ quitting inoculation, 

 "which perpetuates the variolous infection, they luill adopt 

 VACCINATION, ivMch destroy s it. 



I remain, Sec. 



Laborde, D. M. 



Neiv-l^ork, August 29t}j, 

 1805. 



NOTE. 



In a future number of this work, I shall endeavour 

 to collect, into one view, the sentiments of the practi- 

 tioners of medicine, in every part of the United-States, 

 relating to the usefulness and the progress of vaccina- 

 tion, in this great tract of country. In the mean while, 

 it is but just to observe, that the practice has not be- 

 come so extensive as might have been imagined. It 

 is even doubtful, I think, whether, in Pennsylvania, at 

 least, within the last twelve or fifteen months, as 

 great a number of children and otliers have been sub- 

 mitted to the vaccine influence as in tlie twelve or 

 fifteen months preceding. Various circumstances 

 have contributed to arrest the progress of the new 

 practice. Among these may be mentioned, 1. the 

 appearaace of glandular swellings, or cutaneous erup- 

 tions, in many of the children who have been vacci- 

 aiated ; and, 2. the alarms excited by reports of thf 

 communication of small-pox, to persons after they 



