182 Miscellaneous Facts and Observations. 



the left hand, accompanied with a paralysis of that 

 extremity. The fits, at first, were not very frequent; 

 their frequency increased gradually, but with what 

 intervals I could not learn. He was brought into the 

 Hospital by his master, who commanded a trading 

 vessel. The trephine was applied immediately on 

 the depressed part, and when the bone was taken out, 

 a perpendicular spiculum was found growing from its 

 centre, about half an inch in length, which I conceive 

 must have penetrated the coats of the brain. For 

 several days after the operation, the fits were frequent 

 and violent : after the irritation, occasioned by the 

 operation, had 'subsided, they diminished very much, 

 and, for a considerable time previous to his leaving 

 the Hospital, he appeared quite relieved. 



Thomas Massie, M. D. 

 Letter to the Editor, dated London^ 

 February \st, 1805. 



36. Some cases of Small-Pox "have lately appeared 

 in London, after the Vaccine disease. A Committee 

 of Physicians appointed to inquire into the matter, 

 have published a Report, which I would send you if 

 I had a proper conveyance. In the three cases they 

 mention, the vaccine disease had been complete. 

 About two months after, these patients received the 

 small-pox by contagion, attended with all the charac- 

 teristic marks of the disease. They all recovered. 



Dr. Thomas Massie. 

 Letter to the Editor. 



