Revieiv. 173 



" Almost in all the sanguineous, fat, and coloured* 

 subjects, the inflammation about the vaccine pustule 

 appears greater, and more lively, than that which hap- 

 pens to the meagre, yellow, and debilitated : in. the 

 winter season, however, the inflammation appeared more 

 red, the developement of the disease was longer, and 

 the vaccine humour degenerated slower. I have ob- 

 served the contrary during the summer ; in this season, 

 the 7niliary eruptions, appear more frequently. In in- 

 fants of two or three days, vaccination very often has 

 not produced its effect ; and, therefore, it is necessary 

 to operate on them with the greatest care. 



" The same lias happened to me among boys, who 

 were vaccinated whilst they were subject to eruptions of 

 the skiuy or to the Itch. 



" It happened in some subjectsf, that, on the seventh 

 or eighth day, some pustules appeared on parts distant 

 from the innestation, which enlarged, inflamed, and sup- 

 purated almost equal to the vaccine pustule,' leaving a 

 white spot on the part. We cannot attri!)ute this to 

 the contagion of the small-pox, as this city was not onlv 

 free from it at that time, but has been for several years 

 past. Upon this subject, I will relate to you an obser- 

 vation, which is believed, by me, one of the best facts 

 at present on the vaccina. 



• The author, I presume, means those persons, Avho have ■x 

 cuddy complexion. E. C. 



t D. (iiiiseppe Salamone, Maria Spatola, Giuseppe Geli, Agata 

 di Leonardo, Maria Anna Dunari, and T). IVancesco Paolo di Caro. 



