On Cutaneous Absorption. 291 



EXPERIMENT III. 



Recollecting an observation of Haller, that ' as heat 

 increases perspiration, so cold increases absorption,' I 

 determined to enter the bath at as low a temperature as 

 I could bear. In an hour and five minutes, a strong 

 chill and some spasms compelled me to retire. The 

 urine immediately discharged was, as in the two first 

 experiments, pale. At the end of three, and of five 

 hours afterwards, the urine had a little more colour, but 

 the difference was small ; and I am not certain that the 

 sulphat of iron produced any of the brown colour. 

 The urine, at succeeding intervals, had nothing pecu- 

 liar in its appearance. 



EXPERIMENT IV. 



March 25, I continued three hours in the madder- 

 bath. Urine was drawn at the time I left the bath, and 

 at the expiration of five, and of seven, and of fifteen 

 hours afterwards. The first portion was pale, and un- 

 usual in quantity. The second portion exhibited a 

 deeper colour than had appeared in either of the pre- 

 ceding experiments, and, with the sulphat, a very 

 strong purple- brown was produced. The third por- 

 tion, or that taken seven hours after I left the bath, had a 

 feeble tinge of red, and was acted upon in a small de- 

 gree by the sulphat. The fourth portion was natural. 



Blood was drawn from my arm at the end of three, 

 and again at the end of five hours after I left the bath. 



