12 Dr. Rousseau on the 
with whom quinine failed: the fever ceased by the adminis- 
tration of four doses, of three gros each, of the powder of the 
leaves of the holly, in twelve days. A second case, a female, 
aged twenty-five, was ten days ill; treatment continued during 
twenty-five days; fourteen doses, and an equal number of in- 
jections of the holly were administered. The remaining 
twenty cases were ill from two days to five weeks; duration 
of treatment varied from three to fourteen days, and the 
number of doses of the holly from one to ten, each of which 
consisted of from one to three gros of the powdered leaves. 
Twenty Cases of tertian intermittent, fourteen males and 
six females. One case, treated by M. Sr. AmanpE, male, 
aged eighteen, was one year ill; one dose of the powder, 
containing one gros, removed the fever. A second case, (a 
double tertian,) female, aged forty-four, treated by M. 
CoLuiNEav; eight months ill; the fever ceased in five days, 
by four doses, of two gros each, of the powdered holly-leaves. 
A third case, a female, aged twenty-eight, treated by 
M. Macenpie, was ill six weeks; the fever ceased in nine 
days, by seven doses of the same powder. ‘The remaining 
seventeen cases, treated principally by M. Constantin and 
M. Macenpir, were from five to sixteen days ill previous to 
treatment; duration of treatment varied from three to twenty 
days, and the doses of the powder from two to fourteen, each 
containing from one to three gros. 
Twenty Cases of quartan intermittent. One case treated 
by M. Constantin, male, aged twenty-three, was ten 
months ill, and was cured in twelve days, by three doses of 
the powdered leaves. A second case, of a female, aged sixty- 
nine, treated by M. Trianp, was one year ill, during the last 
three months of which the type of the fever changed to a 
double quartan, which was cured in seven days, by four doses, 
of two gros each, of the holly. A third case, of a male, aged 
twenty-four, treated by M. Constantin; period of previous 
illness not stated; duration of treatment, ten weeks; nine 
doses of the decoction of the leaves of the holly were given, 
each dose consisting of two glasses, the first two weeks; 
during the third week, three doses of the powder in wine 
were given. By this treatment the paroxysms became milder, 
though not less frequent; and during the remaining seven 
weeks, eleven injections of a decoction of holly-leaves (only) 
were administered, which effectually removed the fever. 
The other seventeen cases, sixteen male and one female, 
principally treated by M. Consranrin; periods of illness 
varied from six days to two months; duration of treatment, 
from four to thirteen days; doses from one to six of the 
