Holly and Ilicine. 15 
12th. Skin more supple, and the patient appears better; but 
the stupor continues as at first. Ilicine repeated. The parox- 
ysm of fever occurred at eleven a.m., the cold stage lasting for 
three quarters of an hour: he however seemed less sleepy than on 
the 11th. At noon he took another six-grain ilicine pill: yet he 
still had return of coldness in the feet about half-past seven P.M., 
but it was not followed by sweating. 
13th. Two ilicine pills given at six a.m. Coldness of feet came 
on at half-past nine, and lasted till eleven a.m.; this was followed 
by intense heat for about an hour, which then gave way to perspi- 
ration, and the paroxysm (during which he had a yellow fetid eva- 
cuation,) terminated at a quarter-past four P.M. 
14th. Medicines repeated. Access of cold stage at half-past 
ten, lasting only half the time of yesterday's attack, and followed 
likewise by a hot stage of diminished violence: during his waking 
intervals he asked for food. 
15th. Same medicines. Paroxysm rather longer in cold and hot 
stages, but terminated by a more profuse perspiration. He slept 
the greater part of the day. 
16th. Took only one pill of ilicine. Paroxysm did not recur 
till nearly one p.m., and the hot stage was scarcely sensible. 
17th. Twelve grains of ilicine given in two pills. Paroxysm 
delayed till three p.m., and of much less severity. 
18th. Twenty-four grains of ilicine given in four pills, beginning 
at six a.m., and repeating the dose of one pill every three hours. 
A warm bath likewise ordered. 
The same medicines were continued during four days longer, 
but the paroxysm getting weaker and weaker for two days, and 
none at all occurring on the 2Ist or 22d, on the 23d the ilicine was 
discontinued; and on the 6th of August I saw him for the last time, 
when he was completely restored to health. 
Note. One hundred and ninety-eight grains of ilicine were given 
to this patient, besides which cold lotions were applied to the head, 
two blisters for a short time to each side of the chest, and to the in- 
sides of the thighs; warm fomentations to the abdomen; two warm 
baths, clysters, pediluvia, and hot cataplasms to the feet. Inter- 
nally, besides the ilicine, he took ily emollient ptisans, gum 
syrup, capillaire, &c. The above detail shews that this young pa- 
tient was cured by the use of ilicine, without any recourse being 
had to bark. 
Conclusion. 'The end of our labours, for the present, has 
arrived, and assisted as we have been by physicians, the re- 
sults of whose practice we have already given, we may draw 
the following conclusions: 
Ist. That the powder of holly-leaves is, in the cure of 
disease, a valuable medicine, and that nature, always kind, 
seems to have designed it especially for that unhappy class of 
patients which fortune often permits not to consult a Shssiclar, 
