the Juribali. 39 
riments, I concluded that co/d water took up the active parts 
as well as hot. 
This bark not only cures intermittent fevers, but remittents, 
also those of a typhoid malignant kind, and those destructive 
fevers in which the cinchona often does more harm than good. 
In some measure it emulates rhubarb, being cordial and 
purgative according to the dose; it is also a powerful dia- 
_ phoretic, especially if taken warm, by which its value is cer- 
tainly much enhanced as a febrifuge. I have used it in agues 
and in the malignant remittent fevers of the tropics, very 
freely, with the most decisive success, always in the form of 
infusion, commencing at any time or stage of the fever that 
may be present. By infusing an ounce of the bark in a 
quart of hot water, and giving a glassful once in two or three 
_ hours, I think it bids fair to be a useful remedy in smallpox 
_ and measles. 
In a few instances the pulse seemed to be accelerated after 
its use, but was generally rendered slower and fuller; but I 
__ never ascertained the conditions of the patients under which 
these different effects took place, to my own satisfaction. 
Before quitting the present subject, I beg leave to allude to 
an opinion which has long prevailed in my mind, and which 
may be a novel one, or may not; but I have never heard or 
seen it adverted to, and, if correct, it may be worthy the candid 
consideration of the members of this Society and the profession 
at large. 
We must all admit the great value and important advantages 
derived from the Peruvian bark in the practice of medicine. 
It is chiefly in fevers that its uses are to be regarded as pa- 
ramount: but let us consider how far it is entitled to such 
unlimited encomiums as a febrifuge. It is certainly excellent 
‘a8 a tonic, and, as such, is applicable in the treatment of very 
many disorders. It affords one of the most eflicient means of 
: suspending the returns of the common intermittents. I say 
_ ¢ommon, because, in the very malignant and bilious intermit- 
tent fevers of warm countries at least, often met with, it does 
more harm than good ; and in the ardent, typhoid, and remit- 
_ tent fevers, and where most danger lies, we find its uses to 
be the most equivocal, and not unfrequently to produce a 
fatal metastasis on the brain: and in such fevers, those of the 
most dangerous tendency, it is rarely prescribed till the fever 
has subsided, when the skin has become moist, the tongue 
cleaning, sediment in the urine, &c., before the main remedy 
be exhibited; and thus the time must be frittered away 
expectancy, whilst the disease is making its inroads, until it 
