268 On the Poison Tree of Java. (ApRIL, 
in alcohol : having macerated it a few days I exposed it to the open 
air for co-operation, and obtained a small quantity of an elegant 
brown shining resin. A dart was covered with a few grains of this, 
and a fowl wounded in the usual manner. The first three minutes 
after the puncture it remained quiet and appeared drooping. On 
the fourth minute it reeled backward, tottered, and its limbs were 
relaxed. On the sixth minute it appeared to be sleepy, but its 
drowsiness was frequently interrupted by twitchings and startings. 
In eight minutes it tottered, but soon became drowsy again. In 
12 minutes it fell down convulsed and trembling, but soon became 
quiet, and its breathing was quick. On the 17th minute it had 
occasional twitchings in the extremities, and was unable to stand 
erect. On the 20th minute the drowsiness had considerably 
diminished ; it rose, and supported itself, but tottered in attempting 
to walk. From the 30th minute it began to revive, all the effects 
gradually went off, and on the 60th minute it was apparently well. 
Exper. 25.—The following experiment was made at Soorakarta 
in the month of March of the present vear 1812, nearly six years 
after the collection of the oopas in Blambangan. A dog of middling 
size was wounded in the muscles of the thigh with a dart, which 
having been dipped into the oopas, was exposed half an hour to the 
open air, to give the poison time to become dry. During the first 
two minutes he stood quiet, and his appearance only exhibited the 
pain produced by the wound. On thethird minute he was drowsy. 
In five minutes he began to tremble violently and to reel. On the 
seventh minute he fell down head foremost and was convulsed, his 
extremities being stiffly extended: unable to raise himself again, 
the convulsions continued with excessive violence tiil the ninth 
minute, when he died. 
On dissetion his stomach was found natural and contained the 
food lately taken in: all the viscera of the abdomen were also 
natural. In the thorax the venz cave were found completely 
filled, and the aorta partially filled with blood, the lungs stilk 
retained a florid colour. On removing the cranium and exposing 
the brain the whole surface of the dura mater was found inflamed, 
and the vessels were injected with blood; that part covering the 
right lobe in particular was in a state of the highest inflammation ; 
it exhibited externally a livid bluish colour: on the internal surface 
(of the dura mater) the fluid had been forced out of the vessels by 
the violence of the action, and it was covered by a bloody lymph. 
The integuments of the cerebellum were also strongly affected. 
In the vessels of the surface of the brain itself some marks of in- 
flammation were also perceived. On tracing the wound no evi- 
dent marks of inflammation appeared, and the remains of the 
adhering poison were evident along its course. 
Exper. 26.—(To shew the effects of the poison taken internally.) 
To a nearly full grown dog about half the quantity of poison 
generally adhering to a dart was given in a little boiled rice, 
During the first 10 minutes he remained quiet and appeared a little 
