1916] 
Еміс--Үкавт FUNGI 247 
ear mycosis is a very virulent disease, reported the occur- 
rence of Sterigmatocystis nigra, Aspergillus viridescens, A. 
fumigatus, A. albus, A. glaucus, and A. flavescens. The ear 
undergoes a serious catarrh, less frequently conditions of 
purulent discharge. The fungi, Aspergillus fumigatus and 
Sterigmatocystis nigra, investigated by Siebenmann (789), 
grow poorly, if at all, on the normal epidermis. 
There is little mention of fungi appearing in diseases of 
the nose. Schubert (785) reported the occurrence of Asper- 
gillus fumigatus on surface lesions in the nose. In another 
incident, a distiller was so afflicted that both the lower and 
middle nasal cavities were filled with a gray-green secretion 
of a characteristic odor. A microscopic investigation re- 
vealed a hyphomycete with long, single-celled, sickle-shaped 
conidia. No cultures were made, but Ferdinand Cohn pointed 
out the similarity of this fungus to Isaria, certain species of 
which are known to be parasitic on insects. 
Ceratomycosis is of rare occurrence, and only a few cases 
have been described. This condition is usually brought about 
by means of an injury from a falling body infected with fun- 
gous spores. The first incident is that reported by Leber 
(282), in which a farmer forty-five years old, working on a 
threshing-machine, was struck in the eye by an oat scale. 
Berliner and Uhthoff ('83) reported a ceratomyeosis caused 
by a falling pear striking a farmer in the eye. Fuchs (794) 
mentions a case of inflammation in the right eye of a miller 
fifty-three years old and sick with fever, the condition being 
apparently due to an injury and a later infection with As- 
pergillus fumigatus. 
The above-mentioned investigators dealt only with local- 
ized diseases of a single tissue. Zenker, in 1861 (cited by 
Plaut, 03), stated that what had originally occurred as 
thrush on the mucous membrane of a man, had produced 
metastases in the brain in the form of multiple abscesses. 
Grohe, in 1870, injected the spores of moulds into the veins 
of rabbits and presumably obtained metastases of the inner 
organs. Michailow (’11) mentions the occurrence in two 
cases of Asiatic cholera, of fungus-like elements in the cen- 
