[VoL. 3 
266 ANNALS OF THE Missourt BOTANICAL GARDEN 
This fungus is considered by Tokishige (’96) as produe- 
ing in Japan the disease of horses known as *'farcin." It is 
non-pathogenic for rabbits, guinea-pigs, and dogs, by sub- 
cutaneous inoculations. The pathological products of this 
fungus have more effect on animals than inoculations of the 
cultures. Inoculation of this organism in the horse pro- 
duces lesions after varying lengths of time, but without caus- 
ing the death of the animal. 
OOSPORA 
The longest-known fungous disease of the skin is favus, 
which previous to 1839 included a large number of different 
skin affections. When its contagious nature was discovered 
by Schonlein, investigators began searching for the relation 
of fungi to skin diseases. Heusinger in 1826, and Remak in 
1837 (both cited by Virchow, 756) observed mould-like fila- 
ments in the seales of tinea. The latter author in 1847 suc- 
ceeded in growing cultures on apple, again producing the 
characteristic lesions, presumably by inoculating his arm 
with these cultures. Gruby (’43) independently discovered 
three different fungi associated with as many types of ring- 
worm. Two of these fungi were Oospora, and the other was 
Sporotrichum (Microsporon) Audouin. His description of 
these fungi was very good, yet no one at that time suspected 
that, under the name of Porrigo decalvans, he was describ- 
ing fungi which were the cause of ringworn. Very little 
attention was given to these discoveries until Sabouraud be- 
gan his investigations in 1892, which differentiated the many 
varieties of Oospora (Trichophyton) and Sporotrichum ( Mi- 
crosporon). | 
Oospora is often associated with mycosis of the lung and 
with Endomyces albicans in the mouth. Oospora pulmonalis 
brings about a degeneration on the surface of the trachea 
and walls of the bronchia, where white granules are found 
similar to those caused by Actinomyces. The alveolar struc- 
ture is filled with mycelium, and in certain places real ab- 
scesses are found constituted by degenerated tissue filled 
with mycelial debris. In lesions of the mouth, Roger, Bory, 
