1916] 
Emic—Yerast Funct 295 
In experiment 10 animal No. 31 died after twenty days. 
The organism injected was again isolated from the intes- 
tines and the lungs. The condensation of air spaces in the 
lungs of this animal was probably due to post-mortem 
changes. А repetition of this experiment gave negative re- 
sults, as shown by animal No. 32 which lived four months 
without evidence of any injurious effects due to an organism. 
Animal No. 33 received a Jee, injection of a two-day 
sterilized eulture of organism No. 12, grown in beer-wort. 
This animal died in three days. However, a 2-сс. intravenous 
injeetion of a two-day sterilized culture of organism No. 12, 
grown in beer-wort, gave negative results. 
All the remaining twenty-four animals inoculated gave 
negative results, in that no evidence was found of an in- 
jurious effect due to the cultures injected. 
Discussion 
There has been a diversity of opinion in regard to the im- 
portance of fungi as agents in the production of infectious 
diseases. More recent investigations indicate that fungi are 
of secondary importance in the formation of lesions in 
animal bodies, and usually appear secondarily in infected 
tissues. On the other hand, certain species of fungi are to 
be considered of primary importance in those cases in which 
they prove toxic to animals if consumed in large quantities 
on infected foods. 
It is easy to recognize that the parasitic fungus cannot 
prosper with the same degree of success on all animal 
species. Mucor and Aspergillus pneumonomycoses, observed 
frequently in birds, is rarely found in other animals. Certain 
varieties of Sporotrichum (Microsporon) which occur on 
infants, seem to grow with difficulty on animals. Certain 
varieties of Oospora (Trichophyton) are common to man 
and other animals, whereas still other varieties of Oospora 
appear only on man. The changes brought about by the 
disease-producing organisms in the body are quite varied, 
differing quite as much as the morphological and cultural 
characters of the organism when grown outside the body. 
