1896.] MICROSCOPICAL JOUKjnAL. 343 



direct proportion to the severity of the disease or the 

 amount of accumulation. Besides, the serum is apt to be 

 of a dirty ash color. The sticky white corpuscles, the 

 massive fibrin filaments in skeins, and the yeast spores 

 alone or combined, form aggregations, masses, collects, 

 thrombi, and emboli which block uj) the blood vessels of 

 the lungs soonest, because exposed to cold air, the most 

 of any viscus ; the blood vessels contract, and thus arrest 

 the thrombi and form a heterologous deposit, which is 

 called tubercle. 



"The Third Stage, or Stage of Tubercular Deposit. 

 These deposits increase so long as vitality subsists in the 

 tubercle and surroundings. When the vitality ceases, 

 the tubercle softens or breaks down. Sometimes if the 

 process is very slow, and life slightly inheres in it, the 

 proximate tissues undergo fattj^ infiltration, which pre- 

 serves it from readily breaking down. The morphology 

 of the blood is the same for the second and third stages 

 of consumption. » 



" Fourth Stage. Interstitial Death. Morphology of 

 the blood in this stage is the same as in the second and 

 third, save that it becomes more impoverished. The 

 Ked Corpuscles are thinner, paler, much lessened in 

 number, increased in adhesiveness, stickiness and poverty. 

 Devoid more or less of neurine. The white corpuscles 

 are fewer in number, more enlarged ; often ragged and 

 rough. Distended with spores of mycoderma aceti, more 

 adhesive and sticky. The serum. Fibrin filaments are 

 thickened, stronger, more massive and more skeins of 

 them present. The collects of mycodermi aceti are very 

 much larger and more numerous ; in moribund cases, I 

 have seen them so large as almost to fill the field of the 

 microscope. They present anfractuous edges and amoe- 

 boid prolongations, giving them a weird, bizarre aspect 

 which, under the circumstances have a portentous aspect, 



