366 THE AMERICAN MONTHLY [Dec, 



eluded that a part of the cartilage corpuscle, or a por- 

 tion of the body of such a corpuscle, had become trans- 

 formed into hsematoblasts." His statements are illus- 

 trated and have been corroborated by Kassowits and 

 others. In 1873 another paper appeared by this author 

 in which the new formation of blood vessels is described 

 in the process of transformation of cartilaginous into 

 bone tissue, likewise with numerous illustrations in 

 which the hsematoblasts are seen lying in vacuoles of 

 elongated formations of living matter, the future blood 

 vessels. He claims that both blood corpuscles and blood 

 vessels .originate simultanously, the former from isolated 

 lumps of living matter which he termed hsBmatoblasts ; 

 the latter from elongated tracts of living matter hol- 

 lowed out by vacuolation and the accumulation of a 

 liquid, in which the haematoblasts are suspended. Prom 

 this it is evident that — Heitzmann was the discoverer 

 of the hsematoblasts ; the first to correctly describe them, 

 and the first to give them a name. 



In 1877, Gr. Hayem presented to the Academy of Sci- 

 ences of Paris, in brief succession four short papers pub- 

 lished in the Comptes Rendus, Vol. 84, which relate to the 

 red blood corpuscles. In the first paper he spoke of the 

 anatomical features of the blood of the new born. He 

 states that the sizes of the corpuscles are more varied 

 than in the blood of the adult. 



In the second paper he discusses the nature and sig- 

 nificance of the small blood corpuscles. He contradicts 

 a prevalent opinion that these corpuscles indicate a re- 

 trograde change, or atrophy ; on the contrary, he con- 

 cluded from a number of facts which he observed in con- 

 valescent persons after acute wasting diseases, in anaemia, 

 in menstruation, etc., that these small elements which he 

 terms dwarfed corpuscles are young red blood corpuscles 

 incompletely developed. 



In a third paper upon the development of the red 



