Notice of new Medical Preparations. 207 
This peculiar principle, in conformity to the usual nomenclature 
of vegetable proximate principles, I have denominated Sinapine. It 
bears the same relation to mustard that piperine does to pepper, and 
like it is united with an acrid oil, and is otherwise analogous to piper- 
ine in its chemical properties, in not forming salts with acids, &c. 
This differs essentially from the volatile oil obtained by distillation, 
being in every respect superior, and will entirely answer al] the pur- 
poses of the mustard plaster, as a rubefacient. It is simply to be 
applied to the skin, and in a few hours all te effects of the mus- 
tard plaster will be experienced, and vesication may be produced Z 
a second application of the oil. ‘To the country practitioner this oil 
is very valuable: it is inconvenient to carry the mustard about the 
country its activity is soon diminished, and even destroyed, so that, 
if not kept in a close bottle, it becomes inert. As country practi- 
tioners seldom carry this article with them, they are thus frequently 
deprived of the use of aka so important in some cases as to 
be essential to the life of the patien 
' This oil is so concentrated a arene that a small vial, which 
can be conveniently carried with the medicine usually taken by the 
physician, will be sufficient for several applications. action 
will always be uniform and it will not be liable to deteriorate in any 
length of time, it will be found, as a rubefacient, to be a valuable 
substitute for the crude mustard, and I hope will prove a valuable 
addition to the materia medica.* Philadelphia, Feb. 22, 1832.4 
Postscriet—Philad. May 25, 1832.—I have = observed a paper in the Lon- 
don Medical Gazette for Dec. 1831, in which Mr. R. Battley gives a detailed anal- 
ysis of the cinchona. He finds it to consist of. thirteen Abetioc principles, from qui- 
nine to the woody fibre. They all except three. an, = 
phate of otialie’ in consequence of the absence of all the other properties 
luded to, can ae reine be but partially efficient asa medicine. 
es of Mr. Bat 
of Peruvian Bak This gentleman has suggested the sear of =i. the liquor 
cinchona, as a medicine and maintained its decided superiority, since it contains all 
the principles of t the bark above described, except the three sections 
gummy matter, glu and the woody fibre. hi ttley observes, is 
admitted by many competent judges, to be superior to the Pitot 3; and as it is pre- 
Pared by the same process as the quinine, which excludes these three le: 
and-contains all the rest, it would on evaporation, make precisely the same extract, 
as I have described under the name of the precipitated extract of bark. 
* Physicians can be peepee with th ted t of Bark and Oil of Sina- 
ms at Geo. W. Carpenter’s Chemical Sa a 801 Market St., 2 phil 
t Intended for the April No. but did not arrive until it was finish 
‘ 
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