SECT. 71.] SUDORIPAROUS GLANDS. IJI 



thickness of 0015'" to o - o22'" and a cavity of o*oo3"' to 0004'", 

 which frequently extended even into tlic terminal coil; it con- 

 sisted, as avcII as the latter, of the original but now somewhat 

 thickened membrane, continuous with the surface of the cutis, and 

 of an epithelium composed of several layers of pale, polygonal or 

 rounded cells. In like manner I observed, at this period, the 

 glands on the rest of the surface also, about which, in an earlier 

 stage, I can say nothing, and even those of the axilla differed 

 in no respect from the others. From this period, onwards, 

 the development advances rapidly ; the extremity of the gland 

 becomes more and more elongated, rolls itself up, and soon acquires 

 an appearance scarcely differing from that seen in the adult. In 

 newborn infants, the glandular coils in the heel measure o'o6'" 

 to o"07'" (in a child of four months on the heel 006'" to 01'", 

 on the hand 0'i2'") possess much convoluted ducts of o - oi5'" to 

 , 02 / ", and pass, with their excretory ducts (in the cutis o^ooS'" in the 

 rcte Malpighii 0022'"), through the epidermis, in a spiral manner. 



From these facts it results, that the sudoriparous glands are 

 not to be regarded as inversions of the skin ; and are not from the 

 commencement developed as hollow structures, but first make their 

 appearance as simple outgrowths of the mucous layer. By the 

 continued process of cell-multiplication the original rudiments 

 grow deeper and deeper into the skin, assume their peculiar spiral 

 turns, and become differentiated into the glandular coils and the 

 sweat-ducts ; while at the same time a cavity is produced, either by 

 liquefaction of the central portion, which forms, as it Avere, the 

 first secretion, or bv the transudation of fluid between their cells. 

 It is doubtful in what manner the sweat-ducts and sweat-pores in 

 the epidermis are formed ; probably it may be by a metamorphosis 

 in the epidermis itself. According to some examinations I have 

 made [Mikr. A nat. ii. 1, 171), it appears that a development of 

 sudoriparous glands occurs also after the fifth month, but that at 

 birth the full number is present. 



Little is known about the pathological conditions of the sudoriparous 

 j glands. Kohlrausch has found sudoriparous glands of tolerable size {\ a line) 

 1 in an ovarian cyst, along with hairs and sebaceous glands. In Elcpliantiasis 



Qracorum, (1. Simon and Briicke observed enlargement of the sudoriparous 

 I glands, as also v. Bizrensprung, in a species of wart; the latter also saw 



atrophy of the glands in corns, and disappearance of their ducts in the outer 

 •rs of the epidermis. The conditions of the glands in old age, in the 



entire absence of sweat, and in abnormal sweating, is unknown. In a most 

 ; characteristic case of ichthyosis congenita in a new-born infant, which Prof. 



II.MYilltr and I examined, the sudoriparous glands were present. Their 



excretoiv duets, in their course through the epidermis, which reached two 



k :-» 



