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nicotine. (Chart G and H) The patent demonstrates that different 

 percentages of the nicotine salt can be added to blends of 

 tobacco to produce different nicotine concentrations. The 

 control cigarette, the one without any added nicotine, contains 

 1.66 percent nicotine. Adding one percent nicotine salt results 

 in a cigarette with 2.05 percent nicotine. As one increases the 

 amount of nicotine salt sprayed on the tobacco blend, the 

 nicotine content of the tobacco increases. 



In this process, great care is paid to the pH of the smoke 

 because pH affects the bioavailability of nicotine -- that is, 

 how much the body absorbs. The patent demonstrates the 

 technology to increase nicotine content in tobacco by up to 76 

 percent . 



U.S. patent no. 5,065,775 (Chart I) describes another 

 technology that can control the nicotine content of tobacco 

 filler. This involves a process for "modifying the alkaloid 

 content of a tobacco material and, in particular, for providing a 

 processed tobacco material having a controlled nicotine content." 

 (C2:57-60) In the words of the patent "[t]he process of the 

 present invention provides a skilled artisan with an efficient 

 and effective method for changing the character of a tobacco 

 material (e.g., rearranging components of a tobacco material or 

 altering the chemical nature or composition of a tobacco 

 material) in a controlled manner. That is, the process ... can be 

 employed in a way such that changes in the chemical composition 

 of tobacco can be monitored as to occur to a desired degree." 



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