401 



March 25, 1994 Page 13 



Altemacive Nicotine Delivery Devices 



Table 2 lists many of the novel devices that have been 

 patented which imitate the function of cigarettes . Figure 2 is 

 an illustration taken from one of the patents for these devices 

 assigned to Philip Morris. The provision of heat, from 

 electricity, as in the device illustrated in Figure 2, or from 

 combustion, as in Premier, (needed to volatilize 

 pharmacologically effective doses of nicotine) is a common 

 feature . The individual patents and the body of work taken as a 

 whole demonstrate a core concern with delivering material to 

 consumers that is at least relatively free of most if not all 

 toxins other than nicotine. Some patents mention nicotine, some 

 "tobacco flavor," and some only "flavor." The pair from B.A.T. 

 and Brown & Williamson are noteworthy since the British version 

 explicitly discusses nicotine, while the very similar invention 

 patented by its U. S. subsidiary at the same time makes no 

 mention of nicotine or of tobacco. It only discusses "flavor." 



The Imperial Group patent explicitly mentions the inhalation 

 of nicotine as a goal sought by consumers of cigarettes. 



Industry Research on Nicotine 



The Council for Tobacco Research, Philip Morris, and R. J. 

 Reynolds have each funded substantial programs of research on the 

 pharmacology of nicotine. In addition to a program of extramural 

 research, R. J. Reynolds has supported an intramural nicotine 

 laboratory since at least the early 1980s. Funded research has 



