432 



3.584.630 



Ai aMd btrcbi Ike wn* "w«ak adtorbcnu** b micntfcd to 

 taehtd* "pftBor; weak •dterbaaH" tnd "xeondvy WMk ad- 

 tei^tim" u4 fawMf* •4wTt«nt» c om p et ed ctpuMn h««- 

 iat Dm fol)o*l»t chaitcttrtnict- 



1 . Tkc ivrlkc* of th« pottklc* It priacipiDy formed Vy the 

 cMtrior of lb* paitklci, In connm to iHc turftcct 

 Ibrmtd ^ the porM asd finurn. If any. of the paitielM or 

 n« partWat art lirdrophlKc la nauua sad, itniv Iwld 

 aeinaro In a manner whcrabjr the nteotinc k raadOy di»- 

 piaeaaMa by the motetur* praacni bi Wbac«o raeke ecm- 

 kif In conuat llMnvllh; 



2. Tlx panielet do not und to form ehanial bendi »i(h 

 atcoUna^cnd 



i. Tba partlelca absorb nbtunrisU j no nIeotlBC. 



TiM Urm "wea^ adiorbnm" if intended to fatclud* mat«r>- 

 ah harhit a ipacifl« turfaee grcattf than ona asoart meter per 

 iram and the "primary «aak adiorhmtt" and "Mcondary 

 •aak adaorbantt" rvlaie. rnpaetlvaljr, to: 



10 



t} 



«lih lt» addHlve eeaiint. ia appllad eeto a to* or vtb fUttr 

 Mbatrate. le b« lat> cetnpaet and aion rradlly permit (tie 

 Misat« ^ unekt iharathroufti. Tim Ittttr combination cu 

 form part of the Citar tip. 



Tha nieotlna can ba dcpoihtd on to ll>a *«rfac< of the ad- 

 Mfbanl carrier of Dm brantion by any method wblcti pamihi 

 ratatjvtly anlform dstrlbation of the niooUna on the avrCas* of 

 Ibe caniar. WcU-lEnown method* for thi* putpeaa hwhide fan- 

 preinailon of the earrkr by ioakln| R to a nlcotfaw aohition, 

 aptayini h «)th a nicotine toUilion, adierptien en the eanicr 

 of nieetiae from a nicotine lolviion, condaniaiien of nieotinc 

 from vapor pbaae'on the carrier, and iha Bke. For tr«atln| the 

 weak adeerbane avch aa oarbon black, tba nieotino lelatJon 

 «tn be added to Ibe adwrbent and the rcaaltini mUlurt 

 nirred or lumblad in order lo Iboroufhly blend the tame, ha 

 the ciK of »eak idtorbentt of the kydrophIHe adiorbent^ 

 type, pnferabty thcie matcrni* are aoaltad »llh ■ •otuticn of 

 ■Icetine and a ralatively nonpelar aeivani, IbDowed by Otira- 



a. adtorbcnta, the twKaee of which If principally formed by Uob of Ihe miilgra and evaporalloo of any eolvanl ralabtad on 



■kA ttatAv^M* j«r Ik* MA^l^laa anil '" .l. ■ .i a .^? * ^A.^— • 



llie aaterior of the partlelei and 



b. psitklci which are hydrophllic In nature, at aei forth In 

 (I) above and pofuvting the other propettiet which arc 

 ael forth above. 



Tbe weak adaerbent, as It k employed In accordance with 

 the preaenl invaalion, holdi the nkotsne on hi nrfaet durmi 

 >l0ra|C of the tobicro product and rele am the nleotitse mtu 

 Ibe tobacco imcke which form* when the tobacco product I* 

 •moksd. 



Tebocco produeu into which the prcKnt ajfent may be in- 

 cerporatcd inehide filter lip and nonfilter oi|arettn, eigi'i 

 and ci]iarUlei. tt well *> pipe tobacco, pipe fliicn and ether 

 prodtKtt lbrow(h which tobacco emokc paste* en Ih* way to 

 the •aekcr't mouth. The a(onl can be Ineorporatad directly In 

 tht lebaeee or tan be incorpeT*t«d in Ih* Hlur foi tobacco 

 ntioke ?re!trabiy, the a|ent It employed in a filler, nnet thii 

 method remove* any pewiWIity of dcoempealtjon of the 

 nicetiBe darin| eombuttion of the tobacco and tine* the 



25 



the nicetlnecentainint adietbent 



The proportion of nicolina to dry adaorbant will |*B«raUy 

 be be^w«•n 1:20 and 1:1, en a wei|hl baait, reapaetlvaly, and 

 will prefercbty be between lilOand U, ratpecttvely. 



The amount of niootina (in nicotina-adtorbant form) added 

 10 a niiar, on a ci«aret«e batia, nay be from 2.0 lo )3.0 milli-* 

 |rami pel ci«arelte aitd preferably fron 4.0 to 12.0 mUti(rami 

 per ei|arettc, dependini en the amount of nkotioe in the 

 lebaceo. Only lufllelcnl nicotine ehould be added to the 

 )0 tobacco prodaet le raavh In a nkoUna coetcnt in the tobacco 

 •moke appro«imalin| that of a oonvaolienal lebaceo product. 



The amount of nketlne-adaorbant that la added to the 



•obacco win vary depending upon the nkotlne content 



ori(inaUr preaent in the tobacco and upon lb* ntcotin* con- 



)} tent detirtd in the uneke. Oenarally. the nkolhia conunt of 



the tobacco ta imponanUy to a leval whereby there ii 0.1— ).0 



mg. of nkotine In the tmoke per cigarette. 

 , . . One method of dtiermtnlni bow much of a pankular 



ui.u,A^,r,v .,*... rf~~»-,— . — .. — - , «w analya* tBaimeke from the loticco proattet in wJiien the 



M aecflrOMv. -HI- >i.. t»«v... u.„n«««, i, t«. W».. ft»..J picoUna-adwrbant agtm I* ineoT«r*t*d, whkh can b« done 



by coavenlbnal method*, tuch a* I* daaerlbcd in tha "ieurnal 

 of the Awociaiionororrielal AgrkultvralCh«alsu"(vol. «2) 

 (Nov. i. lyjy) en page* 42*— «29. In accordance with Uih 

 '' method, an squeoui lolution of amoka particulate ph*H i> 

 aiaam dijtilled under appropriate cendltiena; thit Is feltewed 



50 



55 



thai ael all adiorbent matertalt will provide a baM for 

 nicotine, which bate wilt hold ihc nicotine during iiorage hui 

 (ram whieh n<«*«ii» e»ft b* eatily rvmovrd Inin » f>»««ing 

 tmeke itream. It ha< been found that the adiorbant, le be ef- 

 facllve ia accerdance with thU biveatien thould be a finely di- 

 vided, weak adiorbenl, ef Itmlud adiorpifvt ability For ca- 

 amptt the w*ak adiorbCnl may be • primary w«ak adtorbcnL 

 luch a> carbon black, lampbbck, gat furnace black, chtnnci 

 black bentonile. tiiania, caklum or magoeaium »nicate, 

 kydrated alumina, and the like. Other primary weak adter- 

 btnta whiob may be employed Include kaolin, menlmnrll- 

 lonke. attapulglte, and rmely divided potyactytenitrile. 

 ■lerocTTOanhte eatlotoae, peiyvinylldeM chloride and timllar 

 •enabaorbenl polymcn. 



teaowbat itrenfer adaorbenia than iboae tat (eith abov* 

 May aho be nacd. Howavar, when aitch adiorbcnu ere cm- 

 ployed, they iheuld have • high alTlnliy fbr water, and can be 

 cstetorkad ai bydrephiUc adaerbeni*. Sueh hydrophUk ad- 

 aorbaau are herein duignad aa "teeondary weak adaorbenli" 60 

 and iMivde material* cich a* lUlca gel alamma, ahiminoall- 

 icaie*. activaied alvmlna, larg* pot* taeiltca and Ih* Hk« The 

 high nottiarc eoaleni of tobacco unek* e*v**t the hydrophil. 

 k adacebent* to lelaaK the nieotin* or elhei lobeceo additive 

 depcaHed o* their tsrfaee, while they lend to adaorb, dee lo «5 

 Iheir tfflnHy to water, the momuic eoniem oi in* amoa*. i n* 

 proportion of Miehe meitiura to adeorbcd, however, it Imell. 



In accerdanee with a prefcned enbediment of Ihe invan- 

 lien, the tobacco treating agent formi a part of a llher lip, or a 

 portjcm of a niter tip, for a •moking article auch at a cigarette 

 The nieoiint ii dcpotited on the finely divided parlkln of the 

 mild adtorbettt or hydrophllie •dMK'wM carrier which ha« the 

 ufwMIItv of heldint lb* nkoiinr in raadlnae* to be dalodged 



70 



by tpactrophoioTTietrk ciamination ef Ik* rctulting dltUllale 



in Ihe ultravlokt ipectral region. 

 Tbe directione for the detaill of thit procedure include Ihe 



following: 

 Ceileet the imoke particulate pkaie (rem 10 tuccauive 

 cigarctui, uing a (tandaid robot unoking procadure (55 

 ml. puff volume taken over a t teoond Inierval, once per 

 minatc) open a glaaa wee) plug or an aquivaleni eeUce- 

 lien medium auliable for tcparaiien of 0. t ft panklct and 

 larger fl«m • gai partkutou phaae nhiura. Strip the 

 akoline alkaloidi from the coUectiea medivm with four 

 10 ml. ponloeaef 005 N MCI. Combine Ihe tcparau ch- 

 ain and dUaie lo eaaeUy 50 ml. with 0.05 N HCI. 

 Traaifar a 1 ml altqtwt of iMa eehrtien to tht pen of the 

 dtnHlation unh. DJcHO approilmatoly 100 ml., and 

 diacard Make Ihe tample in iha unit alkaline by adding a 

 •lat 00 capcale of NaCI and a alM 00 capttil* of NaO N. 

 in that order. Repeat the ditUllaliea and eellcet a eeeond 



too M,l. .MMt*v««. •• TvtU»vft. UUtUI *^^iwHlAk*wl7 90 ,»,!. 



bite a 100 ml. volumetrk flaak to whkh 5 ml. 3 N M,SO, 

 hat praviotialy bean added. Dilute the diitUlale aiaclly to 

 mart with di*til!«d w*lcr, mii wait, and •lamina *p*c- 

 Iropholemelrkany between 250 end 300 m. Correct the 

 abeorbance of iHc unknown aohition ai approximately 

 >M « by a baaalhn **Ucied en th* b**i* of ik* curve 

 Draw a Kna fMm Ih* lewctl point on both aid** of ih* 



