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The Council for Tobacco Research-U.S.A.. Inc. 



SUPPOHTINO BlOMEXHCAL INVESTIGATION 



direction of scientific research has changed. In earlier 

 years, in addition to funding other research areas, the 

 Council funded epidemiological studies, animal inhalation 

 studies, cell culture research, basic clinical research and 

 pathology studies. The Council has also sponsored 

 conferences on various areas of research, such as animal 

 inhalation and cell cultures. In more recent years, the 

 Council's focus has been largely on basic cellular and 

 subcellular research, which today is believed to provide the 

 best opportunity for understanding the processes and 

 mechanisms of diseases, including those that have been 

 statistically associated with smoking. The Council's 

 increasing allocation of grants to basic research reflects 

 the progress of science generally and is consistent with the 

 evolution of research programs at other funding agencies 

 concerned with questions of tobacco use and health, such as 

 the National Institutes of Health, the American Heart 

 Association and the American Cancer Society. 



The Council's financial support has been an 

 important resource for independent research that advances 

 knowledge about tobacco and health. It has sponsored 

 pioneering work in identifying familial cancers, the role of 

 genetic factors in cancer formation, and the identification 



