400 



PRIVATE & CONriPt,fmALT 



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RESEARCH CONT ERE NCE ii^,\i^^^'^'k>-*^'^ '^^ '^ 5 





■?*-►.■ 







-i;?^*-/ HELD AT ICBONBERG 

 l^i^^^- 2nd - 6th TUNE. 1969. '"?«" 



Pr€sem*"> ■'srj'. Green (CI 



(Chair 







sir Charles ElUs- 



» ' '" V r: ^^ .r!./^^' .R. b. Gnif ith 



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*?^?^ 





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^ J C^i'^J^#""- '^- A.,Sanford 



H. Sottorf 



R. "S. Wade , .. ., -^ , - , . - ^ 

 V : r^jr. '.-'X-'r ' -f f . t . 'AV, : . ':-..,•' TT • 



• MINUTES In response to several requests It was decided to JS» ••'•>. 



% ';■'■ expand the minutes somewhat for this Conference, but each mernber*'" 



agreed to be responsible for presenting a fall story to his Company'* 





1. 



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•inanagement If this !s required. ^.•.': .. v c.-- ■ -i**..-^..^ «y.^.-\ACJi.-_- 

 The Coticluslons of the previous Conference were revlewod.' '''^j- ~.~ >•'■ '''■■ 



It was'suggested that the the U.K. representatives should emphasise V, ''^V: 



at the T.S.C. 'SWn-Palntlng Conference" their Interest In the,~^,_" •%. ' /,'.. 



T4A29 comparisonr This appears to be a significant alteration In '-'•"' ''*i^. ^' 



mouse-sVln bloassay reaction brought about by an alteration in' 'i-^^' i-'.^*^ 



tobacco composition. 1' T. R. C. are hampered In following this up by^^' j^'.' -^t? 



Vthe practical difficulties of specifying the actual composltlons'of i* v''.i-'''rr"r 



". T4 and T29. The Coi^erence agreed to Invite T.S.C. to communicate '•"■.'7.'^ /i' 



.'their findings to Dr. GtlffUh of the University of Kentucky, explaining lA-ry^S^. 



,', why they could not follow them up and hoping that the Unlvers 

 Kentucky would use the wide range of tobaccos at their dlsposa 

 known genetic origin, to Investigate how great a variation In "mouse- 



\ skin reaction" could occur within a conventional classification, e.fl. 



..' Virginian flue-cured, Burley, Oriental, etc. Following a discussion 



"/ of the differences In the bloassay results on T.R.C. samples T4 '\- 

 and T29, Dr. Hughes agreed to produce a paper on the laboratory '" 

 tests which could be made to Investigate this. ■''•.' '^■^. \ '■ :' . . 



?iv '.-.-V"^' - '. ^ .•;;.. ?,>;.■ -.:.•'. ■ ^': vsV;>»--'- ■ • 



;■" rr actlonatTori experiments at Harrogate. The Conference devoted 

 some time to considering the value of this line of research. They 

 .(K took note of the T.S.C. paper E 1628, which attempted to s«t out • 

 \ ll*^ p the objectives. The general opinion was that this work should be , 

 •* ^J continued In the hope that It would be possible to Identify specific - 

 "^ inlUators and promoters. ■- '- • •:;--•;•-' .-.f:-'^ -:'f f--'^':'> r 



Ity of ■• i. "'.':., A >* 

 al, of ^''^^S:i:^ 



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