possibility of their being so affected, should be given a 

 careful and systematic examination in order to determine 

 whether or not such infection exists. This inspection 

 should include the mouth, feet, teats, udder, and peri- 

 neum of cows, for the specific lesions of the disease, and 

 the mouth and feet of sheep, other ruminants, and swine. 



Lesions. — The only specific lesion is the vesicular erup- 

 tion in the form of vesicles or blisters with fluid contents, 

 but next in order of importance in diagnosing the disease 

 is the erosion showing abrupt borders which cause it to 

 present a punched-out appearance. Temperatures of all 

 animals in the herd should be recorded. 



Scope of Inspection. — The examination should not 

 be confined to the suspicious animals, but should include 

 all susceptible animals of different species on the farm, 

 and if the suspicion of foot-and-mouth disease is strong, 

 the inspection should extend to animals on adjacent farms. 

 The number of animals affected and a description of the 

 lesions should be noted. Special inquiry should be made 

 into the history of the condition and all information avail- 

 able should be considered with the view of ascertaining if 

 there is any evidence of contagion. 



Report to Chief of Bureau. — In all cases of foot-and- 

 mouth disease, even where there are only slight grounds for 

 suspicion of a new outbreak, the matter should be reported 

 immediately by wire to the chief of the bureau and a de- 

 tailed written report should be forwarded as soon as possible. 

 This report should include a description of the lesions and 

 their location, the number of susceptible animals of each 

 species on the farm, the number of animals of each species 

 affected, the temperature record, and the history, in- 

 cluding the evidence, if any, of contagion. At the same 

 time there should be forwarded to the department, in 

 tightly sealed containers, material immersed in a solution 

 of equal parts of glycerin and boiled water for microscopic 

 and inoculation purposes. This material should include 



