EFFECT OF THYROIDECTOMY OX NITROGENOUS !»IETABOLISiL 481 



10/85 gm. urea ( = 504 gims. X.). And the excess of X. output over 

 intake is accounted for by a loss of weight of ^ kilo. 



After extirpation of both lobes, only 1 grm. of X, was taken in per 

 diem, and &"36 grms. of urea, equivalent to 3"9 grms. X., were excreted. 



There was, therefore, no appreciable difference in the nitrogenous 

 metabolism in this dog after the first operation, but considerable 

 increase in excretion after the second, which was a complete thyroid- 

 ectomy. 



Xo. II. 



Young pup. Wt., 7 kilos. 



In this experiment the total X. was estimated by Kjeldahl in the 

 urine and faeces. 



Xov. 17. — Aromatic sulphates : Total sulphates = '07 2 : 0*491. 



[C/. Xov. 27. „ „ =0-017: 0-475.] 



Xovember 23. — "Wt., 6-5 kilos. 



Xov. 24. — Both lobes removed. The dog was eating a biscuit an 

 hour after the operation. 



Date. 



Water. ' Urine 



Urea. Sp. gr. 



Reac. 



Biscuit. ' 



