482 ' MR J. HERBERT PARSONS. 



November 29.— Wt., 5-7 kilos. 

 / Nov. 27. — Aromatic sulphates : total = 0-017 : 0-475. 



Therefore the aromatic sulphates are greatly decreased, 

 while the total are normal, so that normal sulphates 

 <f are in excess. 



I Nov. 28. — Proteid in urine = 1-428 grm. 

 I Nov. 29. — „ „ =1-65 grm. 



\ No indicau in urine. 



Nov. 25. — Dog quite lively; appetite good. T. 102° F. 

 Nov. 26, 10 A.M. — Weak, listless ; marked tremors, especially behind 

 ears, but also of whole body. T. 101° ; R. normal. 



2 P.M. — Lying down ; rises when called ; does not eat. 

 Nov. 27. — Tremors well marked. Great dyspnoea. 

 Nov. 28, 9.30 A.M. — Marked tremor of masseters; emaciation quite 

 noticeable. Paresis of extensors, especially forelegs. T. 102°*4. 



5 P.M. — Ditto. T. 102°-4. Placed in a'lwarmer room. 

 Nov. 29, 10.30 A.M. — Tremors well marked; more obvious after 

 movement. R. 28; T. 10l°-4. 



4 P.M. — Convulsions. T. 103°. Convulsions began in 

 movements like walking, running, etc., at different rates. Dog lay on 

 side with opisthotonos. R. 52, later 88, and just before a convulsion, 

 20 in seven sec. Corneal reflex active throughout. 

 4.30 P.M. — Dog chloroformed to death. 



Examination of Tissues. 



Blood. — Total solids, 7"25 p.c. Total ash, 1-66 p.c. Urea = 

 0-036 p.c. 



Total N. = 0-672 p.c. No mucin. 



Muscle.— 'UTea = O'lSl p.c. Total N. = 0*185 p.c. 0'16 p.c. 

 kreatin. 



i:iye,-._Urea = 0-041 p.c. Total N. =0-129 p.c. 



jBram.— Urea = 0'067 p.c. Total N. = 0-123 p.c. 



Normal. — Here the total N. intake was 4 grm., and output (in urine 

 and faeces) 4-28 grm., with a loss in weight of ^ kilo. 



After Comjjlete Thyroidectomy. — Total N. intake was 0-8 grm., and 

 output 2-8 grm., with loss of weight 0-9 kilo. 



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