vi Contents. 



Pathogenic germs 40 



Conditions of existence of pathogenic germs in external 



media and in the economy. Sources of infection 40 



Contagious obligatory parasitic microbes 40 



Contagious facultative microbes 41 



Non-contagious facultative microbes 42 



Distribution of pathogenic germs 43 



Modes of contagion 52 



Immediate contagion 52 



Direct contact 53 



Heredity 53 



Mediate contagion 54 



Absorption of pathogenic microbes 55 



II. — Physiology of Pathogenic Microbes. 



Action of microbes upon the organism. '. 61 



Pathogeny of the local changes 61 



Pathogeny of general and remote changes * . . . 63 



Receptivity 65 



Immunity 70 



Reaction of the organism against microbes 74 



Phagocytosis 74 



Bactericidal state 76 



Elimination of microbes 78 



Modifications of virulence 79 



Evolution of the bacterial disease 80 



Incubation 81 



Latent microbism 81 



Specificity of pathogenic microbes 82 



III. — Transformation and Destruction of Pathogenic Microbes 



in their Relation to Hygiene and Therapeutics. 



Morphological and physiological variations of pathogenic 



microbes ; 85 



Attenuation 87 



Preventive inoculations ; vaccinations 94 



Destruction of pathogenic microbes 97 



IV. — Methods of Determination of Pathogenic Microbes. 



Basic and acid colors 104 



Examination of liquids 106 



Examination of organic pulps 107 



Examination of sections 107 



