188 3Ianual of Veterinary Microbiology. 



two degrees. Nevertheless, the appetite only fails a 

 few hours before death. The latter supervenes in 

 thirty-six to forty hours in the guinea pig, forty-eight 

 to sixty in the rabbit; the animal dies in coma or 

 after slight convulsions, and always with a marked 

 depression of temperature. 



The autopsy of animals which have succumbed to 

 the inoculated disease is interesting : the inoculated 

 place is the seat of a jelly-like cedematous infiltration, 

 of a faint red color. This oedema is found in natural 

 cases of charbon when the penetration of the bacte- 

 ridia has occurred at an erosion of the digestive mu- 

 cous membrane : gloss-anthrax, charbonous angina. 

 The corresponding lymphatic glands are tumefied, ec- 

 chymosed, and surrounded by an cedematous zone. 

 The cedematous fluid and the blood are charged with 

 bacteridia. The spleen is much enlarged, difiluent, 

 and dark in color.* 



* [We have little reliable information as to the extent to which 

 anthrax prevails in the United States and Canada. Local out- 

 breaks have been reported from many different quarters, but the 

 microscopical and laboratory investigations necessary to the iden- 

 tification of the disease have generally been lacking. A disease 

 known to the natives as "charbon " prevails in some years as an 

 epidemic among mules in certain parts of Mississippi (also re- 

 ported in Louisiana and Arkansas). This disease was investigated 

 and described as charbon by Veterinarian Creelman, of the Mis- 

 sissippi Agricultural Experiment Station, and the diagnosis con- 

 firmed by the laboratory investigations of Dr. Connoway, of the 

 Missouri Experiment Station. {Miss. Agric. Exper. Sta. Bull. 

 No.ll.) 



Material from the same source (obtained from a cow), examined 

 at Washington, was found to contain the anthrax bacillus. {An. 

 Rep. Bureau of Animal Industry, 1889-1890, jj. 43.) 



An extensive outbreak of anthrax, in Illinois, is reported by 



