Mierobic Diseases Individually Considered. 251 



evolution of the experimental disease. The blood of 

 dogs previously tuberculized possesses properties more 

 active in this respect than that of healthy dogs. These 

 results have been utilized in therapeutics, hsemocyne 

 having been employed in the treatment of human 

 tuberculosis. Tests of the same kind have been made 

 with the blood of the goat. 



Mierobic tuberculosis other than that of Koch. — "We 

 have already said that microbes other than the Koch 

 bacillus are able to engender the special inflammatory 

 reaction which is characteristic of tubercle. Of these 

 we are acquainted with several; we will only refer 

 specially to the tubercle-begetting zoogloea of Malas- 

 sez and Vignal, and to the bacillus of Courmont. 



Zooglceic tuberculosis of Malassez and Vignal. — In 

 studying experimental tubercular lesions of the guinea 

 pig the authors found, in place of Koch's bacillus, 

 micrococci associated in zoogloea. These germs are 

 not stained by Ehrlich's method; they maybe demon- 

 strated by the following process : 



Sections are left during two or three days in a mix- 

 ture of: 



Two per cent solution of carbonate of 



soda, ...... 10 volumes. 



Saturated aniline water, . . 5 " 



Absolute alcohol, .... 3 " 



Solution made with 9 vols, of distilled 

 water and 1 vol. of concentrated so- 

 lution of methylene blue in 90 per 

 cent alcohol, .... 3 " 



They are washed with water, dehydrated in abso- 



