254 Manual of Veterinary 31icrohiology. 



Courmont's bacillus, therefore, produces a tubercu- 

 losis in the ox; the lesions of the ox have direct 

 tubercle begetting action on the rabbit but not on the 

 guinea pig, except under the special conditions men- 

 tioned above. We know, however, that the guinea 

 pig is more sensitive to mammalian tuberculosis than 

 the rabbit, hence, besides the character of the bacil- 

 lus, there is a manifest diiFerence between the two 

 diseases. Furthermore, the experimental tubercu- 

 losis obtained in the guinea pig by the subcutaneous 

 inoculation of Koch's bacillus develops so slowly 

 that, on an average, the lung is invaded only at the 

 end of two months; with the bacillus of Courmont, 

 as also with the zoogloese of Malassez and Vignal, 

 the guinea pig becomes tuberculized in less than ten 

 days. Generally, in the rabbit, the duration of Cour- 

 mont's tuberculosis is almost the same as that of 

 Koch's tuberculosis. Another character important to 

 notice is the presence of Courmont's bacillus in the 

 blood of subjects tuberculized by means of this bacil- 

 lus. Finally, the disease generalizes without infecting 

 the lymphatic glands. 



Glanders. 



■ Glanders is an infectious and contagious disease, 

 with progressive course, characterized by circum- 

 scribed and multiple alterations localized in the re- 

 spiratory mucosa (glanders), or in the skin (farcy). 

 These two localizations may coexist, in which case 

 we have to do with the disease glanders-farcy. The 

 disease is peculiar to solipeds : horse, ass, and mule; 

 it may also develop in man as a result of accidental 

 inoculation with virulent products coming from one 



