Microhic Diseases Individually Considered. 815 



the streptococcus of Chantemesse and Delamotte. 

 The microhe of Schiitz and those of Galtier and Vio- 

 let do not take the Gram, whilst all the others do. 

 Most of them are facultative anaerobes. All are 

 pathogenic for the rabhit, which contracts a rapidly 

 fatal disease : the blood is decomposed and the color- 

 ing matter of the corpuscles, thus set free, passes 

 into the serum, giving to the latter a red tinge, which is 

 communicated to the liquids of the serous membranes 

 and to the viscera in contact with these liquids ; the 



sotn&times contains a fibrinous exudate ; the lung is much con- 

 gested, this condition being sometimes complicated with intersti- 

 tial hemorrhages; the blood often escapes into the bronchi un- 

 changed ; once only was hepatization present and that in a rabbit 

 whicVi had survived five days. 



The guinea pig is a very unreliable reagent for the streptococ- 

 cus, whilst the dog is unaffected by it. 



Inoculation of 5 cc. of a culture into the lung of a glandered 

 horse caused a very intense febrile reaction ; the temperature rose 

 from 38-5° to 40-1° and remained at this figure during several 

 days, whilst the animal showed complete inappetence and great 

 prostration ; it usually kept the recumbent position and had to be 

 assisted to its feet. It was impossible to detect any symptoms of 

 pulmonary disease. At the autopsy, made ten days later, nothing 

 was found at the place of inoculation, but four pneumonic centers 

 existed on the lower border of the lobes of the organ. Three of 

 these had the dimensions of a five franc piece, the fourth that of 

 a child's hand. At these places the lung was very consistent, of a 

 deep brown color, and manifestly hepatized. Two other horses 

 received an injection of a five days old culture in the lung. At 

 the autopsy, made on the following day in one case, and on the 

 third day in the other, the place of inoculation showed an inflam- 

 matory focus large as a man's fist ; the hepatized lung was dotted 

 with very fine hemorrhagic points and the visceral pleura infil- 

 trated with plastic serosity and notably thickened. In these le- 

 sions the streptococcus of the cultures was found. None of these 

 .last cases showed any febrile reaction. 



