84 Notes from the Physiological Laboratory 



almost unbearable. He was ordered to remain in 

 bed, and twenty grains of salicylic acid were rubbed 

 into a paste with olive oil, and gently smeared in 

 each axilla. Four hours thereafter, the patient felt 

 somewhat better; and the urine examined at this 

 time showed the presence of the drug upon the ap- 

 plication of the ferric chloride test. At noon, on 

 the following day, the patient reported himself as 

 entirely well. 



CASE II. Female, set. 60, suffering from fre- 

 quently-recurrent and severe rheumatic pains in the 

 shoulder. The method of treatment used in the 

 preceding case was here employed, and the patient 

 reported marked relief on the following day, at 

 which time, also, the drug was found in her urine. 



CASE III. Female, set. 28. Rheumatic pains 

 in arm and shoulder. Application as in previous 

 cases. The drug here proved a decided irritant to 

 the very sensitive skin, and was removed in some 

 fifteen hours. Results negative. Urine not exam- 

 ined. Pain and stiffness subsequently disappeared 

 after the exhibition of large doses of sodium sali- 

 cylate internally. 



CASE IV. Male, set. 25, frequently subject to 

 rheumatism in the left shoulder, and always re- 

 lieved by the internal use of sodium salicylate ; was 



