II 



Each student has to produce the following morbid 

 states in frogs and to make microscopical examination 

 of the same in vivo: 



3. Venous engorgement and bleeding per diapedesin 

 and per rhexin | tongue, web|. 



4. Stasis and alterations of vessels (contraction and 

 dilatation) from chemical causes [tongue, web, lung). 



5. Thrombosis (red and white thrombi; mechanical 

 and chemical influence) [lung, mesentery]. 



G. Embolism [lung|. 



7. Local hypenemia and amumia (by section and irri- 

 tation of nerves, etc.) [tongue, web]. 



8. Ischiemia and its consequences (inflammation, ne- 

 crosis) [tongue]. 



9. Inflammation (produced by cautery, denudation, 

 etc.) [tongue, cornea]. 



10. Oedema (hydremic plethora, etc. in frogs). 

 Some of these experiments are supplemented by 

 demonstrations on warm-blooded animals: for ex- 

 ample, experiments on the rabbits' ear, guinea-pigs' 

 mesentery, etc. are made to illustrate inflammation. 



/ - 



11. As an introduction into kymographic experiments 

 with the frog's heart some practical work with 

 normal and poisoned muscle preparations is done 

 [gastrocnemius, tongue]. 



12. Different cardiographic experiments on a frog's 

 heart under normal and pathological circumstances 

 (poisons, irritation of vagus, etc.). 



13. Artificial circulation in a removed frog's heart. 

 To this is added a series of experiments in patholo- 

 gical conditions of the blood such as 



1). Changes of the red corpuscles produced by 



poisons, burns, anaemia, etc. 

 2). Hyperleucocytosis and hypoleucocytosis. 



15 



