Ill 



blood can fix 0,04 cc. of a 0,1 n NH 3 or NaOH solution. 

 The amounts used in these experiments will, as is shown 

 below, be much greater, so that without great errors, 

 the active amounts of base may be considered constant. 

 In all cases in the calculation, the said amount has been 

 substracted from the amount added. 



But on the other hand that quantity of blood which 

 has not been hiemolysed, decreases during the reaction. 

 It is natural to suppose that the amount transformed 

 per unit of time, is proportionate to the amount of 

 blood corpuscles present. If therefore the number of 

 these arbitrarily be fixed at 100 to begin with, and at a 

 given lime at 100 x, the following differential equation 

 results: 



^T = K (100 -x) 



or integrated, where I signifies time 



100 Xn 



All the calculations of velocities of reaction, deter- 

 mined by means of the first methods have been made 

 according to this equation. In these calculations the ordi- 

 nary logarithms have been used, so that K is 2,3025 times 

 greater than Kj. As an example some determinations 

 of the velocity of the reaction of ammonia at 37 C may 

 be ([noted. 



I 

 A. ().7o cc. l /3o n NH :i 



B. 0.5 cc. Vi 



27 



