Ill 



thus a decreasing action upon haemolysis. They behave 

 as if they combined partially with the bases and with 

 the tetanolysin, giving in this way weaker hiumolysiiig 

 agents. Therefore it is characteristic of all these proteid 

 bound hsemolytic bodies that the increase of haemoly- 

 sis with increasing amounts of the hsemolysing body 

 is progressing less rapidly than for the pure bases or 

 lysin. This effect increases - - as may be expected - 

 with the amount of proteid. 



In this chapter we have dealt with the action of 

 a few so to speak neutral bodies upon the haemolysis. 

 This action is very different in different cases and 

 must therefore be ascribed to different causes. 



As to the action of neutral salts upon the strong 

 bases, it is similar in all of them (when present in 

 equivalent amounts). This is most easily explained by 

 supposing that the combination of strong alkalies with 

 red blood corpuscles behaves as weakly dissociated sail 

 like acetate ot copper or potassiumstibiotartrate or like 

 a rather strong base, the degree of dissociation of which 

 is decreased through the addition of salt. 



The same applies to the effect of ammonia salts upon 

 the hcemolytic action of ammonia, but the effect is here 

 much stronger. In other terms, the combination of am- 

 monia with blood corpuscles is much less dissociated 

 than the combinations of the strong bases. It is only 

 the dissociated molecules of these salt like combinations 

 which react (or at any rate they react much quicker 

 than the undissociated). Therefore the velocity of reac- 

 tion is decreased through the addition of salts, contain- 

 ing the same ions. We might also suppose that some 

 soluble product of the combination of the bases with 

 the red blood corpuscles was formed and that this was 



52 - 



